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Expression analysis and mass spectrometric structure characterization reveals unknown ezrin truncations in lymph node metastases of breast cancer patients

机译：表达分析和质谱结构表征揭示乳腺癌患者淋巴结转移中未知的Ezrin截短

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Most breast cancer-related deaths are due to metastases derived from the primary tumor. In breast cancer the axillary lymph node status is an important prognostic factor [1]. Metastastic potential of tumors is crucially influenced by cytoskeleton remodeling and cell adhesion of (circulating) tumor cells. Ezrin is involved in cell adhesion, motility, morphogenesis, and signaling pathways [2].

机译：与源自原发性肿瘤的转移，大多数乳腺癌相关的死亡者都是由于衍生的转移。在乳腺癌中，腋窝淋巴结状态是重要的预后因素[1]。肿瘤的转移潜力至关重要的是（循环）肿瘤细胞的细胞骨架重塑和细胞粘附性关键。 Ezrin参与细胞粘附，运动，形态发生和信号传导途径[2]。

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《ASMS Conference on Mass Spectrometry and Allied Topics》|2014年||共1页
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Claudia Rower; Christian George; Toralf Reimer; Bernd Gerber; Michael O. Glocker;
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中图分类 TB994.5-53;
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专利

1. 浸润性乳腺导管癌组织中Ezrin和钙粘素E的表达与淋巴结转移的关系 [J] . 李琼, 吴明富, 宋安萍, 癌症（英文版） . 2006,第003期
2. Distinct Ezrin Truncations Differentiate Metastases in Sentinel Lymph Nodes from Unaffected Lymph Node Tissues, from Primary Breast Tumors, and from Healthy Glandular Breast Tissues [J] . Claudia R?wer, Christian George, Toralf Reimer, Translational Oncology . 2018,第1期

机译：独特的Ezrin截断区分前哨淋巴结中未受影响的淋巴结组织，原发性乳腺肿瘤和健康的腺性乳腺组织中的转移
3. Risk Stratification For Axillary Lymph Node Metastases in Breast Cancer Patients What Clinicopathological and Radiological Factors of Primary Breast Cancer Can Predict Preoperatively Axillary Lymph Node Metastases? [J] . Yun Seong Jong, Sohn Yu-Mee, Seo Mirinae Ultrasound quarterly. . 2017,第1期

机译：乳腺癌患者中腋窝淋巴结转移的风险分层，原发性乳腺癌的临床病理和放射源因素可以预测术前腋窝淋巴结转移吗？
4. Expression of p16 in lymph node metastases of adjuvantly treated stage III colorectal cancer patients identifies poor prognostic subgroups: a retrospective analysis of biomarkers in matched primary tumor and lymph node metastases. [J] . Karamitopoulou E, Zlobec I, Koumarianou A, Cancer: A Journal of the American Cancer Society . 2010,第19期

机译：在经过辅助治疗的III期大肠癌患者的淋巴结转移中p16的表达确定了预后不良的亚组：对匹配的原发肿瘤和淋巴结转移中生物标志物的回顾性分析。
5. Expression analysis and mass spectrometric structure characterization reveals unknown ezrin truncations in lymph node metastases of breast cancer patients [C] . Claudia Rower, Christian George, Toralf Reimer, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：表达分析和质谱结构表征揭示乳腺癌患者淋巴结转移中未知的Ezrin截短
6. Evaluation of pathologic parameters and published nomograms in predicting non-sentinel lymph node metastases in female breast cancer patients with positive sentinel lymph nodes. [D] . Murch, Lisa Elaine. 2007

机译：在前哨淋巴结阳性的女性乳腺癌患者中预测非前哨淋巴结转移的病理参数和公布的列线图评估。
7. Distinct Ezrin Truncations Differentiate Metastases in Sentinel Lymph Nodes from Unaffected Lymph Node Tissues from Primary Breast Tumors and from Healthy Glandular Breast Tissues [O] . Claudia Röwer, Christian George, Toralf Reimer, 2018

机译：不同的埃兹林截断区分前哨淋巴结中未受影响的淋巴结组织原发性乳腺肿瘤和健康的腺乳腺组织中的转移
8. Expression of ALDH1 in axillary lymph node metastases is a prognostic factor of poor clinical outcome in breast cancer patients with 1–3 lymph node metastases [O] . Nogami, Tomohiro, Shien, Tadahiko, Tanaka, Takehiro, 2012

机译：腋窝淋巴结转移中ALDH1的表达是乳腺癌患者1-3淋巴结转移的临床预后不良的预后因素

Expression analysis and mass spectrometric structure characterization reveals unknown ezrin truncations in lymph node metastases of breast cancer patients

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