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Discrimination of cyanobacterium Microcystis aeruginosa by MALDI-MS and analysis of its genetic diversity

机译：MALDI-MS对微囊杆菌微囊杆菌铜绿假单胞菌的鉴别及其遗传多样性分析

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Microcystis aeruginosa, one of the most prevalent bloom-forming cyanobacteria, which produce hepatotoxic microcystins, has become a serious problem. Efforts employing gene technologies have revealed that there are high genetic diversity and clonality in M. aeruginosa. Also, both toxic and non-toxic colonies coexist in nature. Many attempts have been made to develop a rapid typing method to distinguish toxic M. aeruginosa from non-toxic strains, even employing microcystin genes themselves as markers. However, genetic similarity and toxicity are not always correlated. A higher resolution typing method is required to overcome the problem.
机译：Microcystis铜绿假单胞菌是一种产生肝毒性微囊藻的最普遍的盛开的蓝藻之一，已成为一个严重的问题。采用基因技术的努力揭示了M.铜绿假单胞菌的高遗传多样性和克隆性。此外，毒性和无毒菌落的性质上共存。已经制定了许多尝试来开发一种快速打字的方法，以区分来自无毒菌株的有毒M.铜绿假单胞菌，甚至用微囊藻基因本身作为标记。然而，遗传相似性和毒性并不总是相关的。需要更高的分辨率打字方法来克服问题。

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