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TRAPPED ION MOBILITY SPECTROMETRY AS NOVEL SEPARATION TECHNIQUE FOR THE INVESTIGATION ON ISOMER FORMATION DURING THE SIMULATION OF PHASE I METABOLISM BY MEANS OF ELECTROCHEMISTRY/MASS SPECTROMETRY

机译：被捕获的离子迁移光谱法作为新型分离技术，用于通过电化学/质谱法模拟I相的代谢模拟期间的异构体形成

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Electrochemistry/mass spectrometry (EC/MS) has evolved as a valuable and purely instrumental approach in mimicking the phase I metabolism of xenobiotics. Due to the formation of isomers after the electrochemical treatment, the development of a separation method in order to distinguish between them is required. For this purpose trapped ion mobility spectrometry (TIMS) enables a novel and faster approach for the separation of oxidation products.

机译：电化学/质谱（EC / MS）已经发展为模拟Xenobiotics的I阶段代谢的有价值纯粹的仪器方法。由于在电化学处理之后形成异构体，需要开发分离方法以区分它们。为此目的被捕获的离子迁移光谱法（TIMS）使得一种新颖的和更快的方法来分离氧化产品。

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《International Mass Spectrometry Conference》|2018年|p628-1245|共2页
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Jens Fangmeyer; Simon Gereon Scheeren; Robin Schmid; Uwe Karst;
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正文语种
中图分类分析化学;
关键词
Electrochemistry; Metabolism; Trapped Ion Mobility Spectrometry; Liquid chromatography; Hyphenation;

机译：电化学;新陈代谢;被捕获的离子迁移光谱法;液相色谱;连字;

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1. Comprehensive lipidomic analysis of human plasma using multidimensional liquid- and gas-phase separations: Two-dimensional liquid chromatography–mass spectrometry vs. liquid chromatography–trapped-ion-mobility–mass spectrometry [J] . Anna Baglai, Andrea F.G. Gargano, Jan Jordens, Journal of chromatography, A: Including electrophoresis and other separation methods . 2017,第期

机译：使用多维液相 - 气相分离的人血浆综合脂质分析：二维液相色谱 - 质谱与。液相色谱 - 捕获离子迁移率质谱法
2. Recent advances in biological separations using trapped ion mobility spectrometry - mass spectrometry [J] . Fouque Kevin Jeanne Dit, Fernandez-Lima Francisco TrAC: Trends in Analytical Chemistry . 2019,第期

机译：使用被捕获的离子迁移光谱法 - 质谱法的生物分离的最新进展
3. New Vistas for Mass Spectrometry-Based Proteomics and Biotechnology: Rapid Two-Dimensional Separations Using Gas-Phase Electrophoresis/lon Mobility-Mass Spectrometry [J] . John A. McLean, David H. Russell American Biotechnology Laboratory . 2005,第6期

机译：基于质谱的蛋白质组学和生物技术的新视野：使用气相电泳/离子淌度质谱进行快速二维分离
4. TRAPPED ION MOBILITY SPECTROMETRY AS NOVEL SEPARATION TECHNIQUE FOR THE INVESTIGATION ON ISOMER FORMATION DURING THE SIMULATION OF PHASE I METABOLISM BY MEANS OF ELECTROCHEMISTRY/MASS SPECTROMETRY [C] . Jens Fangmeyer, Simon Gereon Scheeren, Robin Schmid, International Mass Spectrometry Conference . 2018

机译：被捕获的离子迁移光谱法作为新型分离技术，用于通过电化学/质谱法模拟I相的代谢模拟期间的异构体形成
5. Separation of combinatorial library isomers using ion mobility/mass spectrometry techniques. [D] . Hilderbrand, Amy E. 2005

机译：使用离子迁移/质谱技术分离组合库异构体。
6. Enhancing glycan isomer separations with metal ions and positive and negative polarity ion mobility spectrometry-mass spectrometry analyses [O] . Xueyun Zheng, Xing Zhang, Nathaniel S. Schocker, -1

机译：通过金属离子和正负离子迁移率质谱-质谱分析增强聚糖异构体分离
7. Selecting and identifying gas-phase protonation isomers of nicotineH+ using combined laser, ion mobility and mass spectrometry techniques [O] . Samuel J. P. Marlton, Benjamin I. McKinnon, Boris Ucur, 2019

机译：使用组合激光，离子迁移率和质谱技术选择和识别尼古丁+的气相质量异构体

TRAPPED ION MOBILITY SPECTROMETRY AS NOVEL SEPARATION TECHNIQUE FOR THE INVESTIGATION ON ISOMER FORMATION DURING THE SIMULATION OF PHASE I METABOLISM BY MEANS OF ELECTROCHEMISTRY/MASS SPECTROMETRY

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