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CAN PATIENT PROGRESS MODELLING INFORM THE MANAGEMENT OF CANCER PATIENTS?

机译:患者进步建模可以告知癌症患者的管理吗?

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Patient progress modelling was originally developed in the context of the analysis of leukaemia drug trials. Typically, such modelling involves determining a finite number of different health states in which a patient might be at various times, deriving appropriate sojourn time distributions and transition probabilities to reflect the transfers made between these and then the derivation of time-dependent state probabilities. We describe the development of a "calculation engine" that can be used within Microsoft Excel to facilitate such modelling and its potential application concerning the use of chemotherapy following curative surgery for lung cancer.
机译:患者进展建模最初在白血病药物试验分析的背景下开发。通常,这种建模涉及确定有限数量的不同健康状态,其中患者可能在不同时间,导出适当的索州时间分布和转换概率,以反映这些概率之间的转移,然后是时间相关的状态概率的推导。我们描述了可以在Microsoft Excel中使用的“计算发动机”的发展,以促进这种建模及其在肺癌治疗手术后使用化疗的潜在应用。

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