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首页> 外文会议>European Meeting on Supercritical Fluids >ON-LINE SOLUTE CONCENTRATION DETERMINATION IN SC-CO_2 BY APPLYING SPECTROPHOTOMETER TECHNIQUES
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ON-LINE SOLUTE CONCENTRATION DETERMINATION IN SC-CO_2 BY APPLYING SPECTROPHOTOMETER TECHNIQUES

机译：通过应用分光光度计技术在SC-CO_2中在线溶质浓度测定

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摘要

Coating or encapsulation of fine particles can produce tailored surface properties, which is of great interest in pharmaceutical, cosmetic, food, and agrochemical industries. Encapsulation of active compounds may allow enlarging product life, preventing degradation, improving handling conditions and providing sustained release properties. Encapsulation processes based on supercritical fluids (CO_2 especially) provide important advantages compared to other methods such us smaller particle diameters, narrow particle size distribution, or the possibility of defining different morphologies as a function of process conditions. In this context, a project was conceived to study several aspects concerning microencapsulation of substances with SC-CO_2 in order to develop an innovative process. As a result, solute concentration after microencapsulation was pointed out as an important parameter to be controlled. In this work, spectroscopy techniques have been applied on-line at a laboratory scale supercritical fluid encapsulation equipment has been used to carry out the experimental concentration measurement. Experimental research showed that the designed and built-up system may be applied at SC-CO_2.
机译：细颗粒的涂层或封装可以产生量身定制的表面性质，这对药物，化妆品，食品和农用化学行业具有很大的兴趣。活性化合物的封装可以允许扩大产品寿命，防止降解，改善处理条件并提供缓释性能。与其他方法相比，基于超临界流体（CO_2的封装过程提供了与其他方法如此较小的粒径，窄粒度分布的窄粒径分布或定义不同形态的可能性，这提供了重要的优点。在这种情况下，设想项目研究有关SC-CO_2的物质微胶囊的几个方面，以制定创新过程。结果，将微囊化后的溶质浓度指出作为待控制的重要参数。在这项工作中，在实验室规模的超临界流体封装设备上已经在线施加光谱技术已经用于进行实验浓度测量。实验研究表明，设计和内置系统可以应用于SC-CO_2。

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