Multiple Myeloma in a pig - a case report

机译：猪中的多发性骨髓瘤 - 一个案例报告

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Multiple myeloma or plasmacytoma is a neoplastic proliferation of plasma cells [1]. Plasma cell tumours are rare in domestic animals [2]. The bodies of the vertebrae are common locations for plasma cell diseases such as multiple myeloma. It is a disseminated neoplasm characterised by the involvement of multiple bones, bone marrow infiltration and monoclonal immunoglobulin synthesis. Secondary invasion of the epidural space is infrequent but can cause neurological symptomes. Spinal cord compression due to pure intradural plasma cell infiltration is very rare [3]. Plasma cell neoplasm was first reported in a 8-month old female pig with different leucemic tissue infiltrations [4]. The presented case is aimed to demonstrate characteristic clinical and pathohistological findings.

机译：多种骨髓瘤或血浆是血浆细胞的肿瘤增殖[1]。血浆细胞瘤在家畜中是罕见的[2]。椎骨的椎体是血浆细胞疾病如多种骨髓瘤的常见位置。它是一种散发的肿瘤，其特征在于多个骨骼，骨髓浸润和单克隆免疫球蛋白合成的参与。硬膜外空间的二次入侵是不常见的，但会导致神经系统症状。由于纯净的内部血浆细胞浸润引起的脊髓压缩非常罕见[3]。第一次在一个8个月的雌性猪中首次报道血浆细胞肿瘤，其具有不同的幼虫组织渗透[4]。呈现的案件旨在展示特征临床和病理学发现。

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《Congress ofthe International Pig Veterinary Society》|2008年||共1页
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U RINTISCH; B MUNZER; R KLOPFLEISCH; KH LAHRMANN;
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中图分类 S828-532;
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1. Lenalidomide, adriamycin, and dexamethasone (RAD) in patients with relapsed and refractory multiple myeloma: a report from the German Myeloma Study Group DSMM (Deutsche Studiengruppe Multiples Myelom). [J] . Knop S, Gerecke C, Liebisch P, Blood: The Journal of the American Society of Hematology . 2009,第18期

机译：来那度胺，阿霉素和地塞米松（RAD）在复发和难治性多发性骨髓瘤患者中的作用：德国骨髓瘤研究小组DSMM（Deutsche Studiengruppe Multiples Myelom）的报告。
2. Multiple Myeloma Masquerading as Ovarian Carcinosarcoma Metastases: A Case Report and Review of the Approach to Multiple Myeloma Screening and Diagnosis [J] . Robert Stuver, Alec Petersen, Thomas A. Guerrero-Garcia, Case Reports in Hematology . 2018,第1期

机译：伪装成卵巢癌肉瘤转移的多发性骨髓瘤：病例报告和多发性骨髓瘤筛查和诊断方法的回顾。
3. Metastatic cutaneous plasmacytoma: a case report associated with IgA lambda multiple myeloma and a review of the literature of metastatic cutaneous plasmacytomas associated with multiple myeloma and primary cutaneous plasmacytomas. [J] . Kato N, Kimura K, Yasukawa K, The Journal of dermatology . 1999,第9期

机译：转移性皮肤浆细胞瘤：与IgAλ多发性骨髓瘤相关的病例报告，以及与多发性骨髓瘤和原发性皮肤浆细胞瘤相关的转移性皮肤浆细胞瘤的文献综述。
4. Multiple Myeloma in a pig - a case report [C] . U RINTISCH, B MUNZER, R KLOPFLEISCH, Congress ofthe International Pig Veterinary Society . 2008

机译：猪中的多发性骨髓瘤 - 一个案例报告
5. A study of microRNAs associated with multiple myeloma pathogenesis and microRNAs/TP53 feedback circuit in human cancers, multiple myeloma and glioblastoma multiforme. [D] . Suh, Sung-Suk. 2012

机译：在人类癌症，多发性骨髓瘤和多形性胶质母细胞瘤中与多发性骨髓瘤发病机制相关的microRNA和microRNA / TP53反馈回路的研究。
6. Multiple Myeloma Masquerading as Ovarian Carcinosarcoma Metastases: A Case Report and Review of the Approach to Multiple Myeloma Screening and Diagnosis [O] . Robert Stuver, Alec Petersen, Thomas A. Guerrero-Garcia, 2018

机译：伪装成卵巢癌肉瘤转移的多发性骨髓瘤：病例报告和多发性骨髓瘤筛查和诊断方法的回顾。
7. Multiple Myeloma Masquerading as Ovarian Carcinosarcoma Metastases: A Case Report and Review of the Approach to Multiple Myeloma Screening and Diagnosis [O] . Robert Stuver, Alec Petersen, Thomas A. Guerrero-Garcia, 2018

机译：伪坐卵巢癌瘤转移的多发性骨髓瘤：案例报告和对多发性骨髓瘤筛查和诊断方法的审查

Multiple Myeloma in a pig - a case report

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