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BioCAD in tissue science and engineering

机译：组织科学与工程中的生物碳

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摘要

Tissue Engineering, the science and engineering of creating functional tissues and organs for transplantation, integrates a variety of scientific and engineering disciplines to produce physiologic ldquoreplacement partsrdquo for the development of viable substitutes which restore, maintain or improve the function of human tissues. In the success of tissue engineering, three-dimensional (3D) scaffolds play important roles as extra-cellular matrices onto which cells can attach, grow, and form new tissues. Modeling, design and fabrication of tissue scaffolds to meet multiple biological and biophysical requirements is always a challenge in regenerative tissue engineering. BioCAD in tissue engineering is broadly classified into the following three major applications: 1) computer-aided tissue modeling, including 3D anatomic visualization, 3D reconstruction, computer-aided design (CAD) of tissue models and bio-physical modeling for surgical planning and simulation; 2) computer-aided tissue scaffold informatics and biomimetics; and 3) bio-manufacturing for tissue and organ regeneration.
机译：组织工程，创建功能组织和器官进行移植的科学和工程，整合各种科学和工程学科，为生理Ldquoreplacement partsrdrdquo进行了开发，恢复，维持或改善人组织的功能。在组织工程的成功中，三维（3D）支架起到重要的作用作为细胞可以附着，生长和形成新组织的额外细胞基质。组织支架的建模，设计和制作满足多种生物和生物物理要求始终是再生组织工程中的挑战。组织工程中的生物态广泛分为以下三个主要应用：1）计算机辅助组织建模，包括3D解剖可视化，3D重建，计算机辅助设计（CAD）组织模型和外科手术规划的生物物理建模; 2）计算机辅助组织脚手架信息学和生物体; 3）组织和器官再生的生物制造。

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