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PATHOPHYSIOLOGY OF SPINAL CORD INJURY

机译：脊髓损伤的病理生理学

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The spinal cord can be injured through three major pathological mechanisms: i) contusion, in which there is a rapid on/off deformation of the spinal cord (similar to that resulting from a hammer blow); ii) compression, in which the spinal cord undergoes persistent deformation; and, iii) direct impairment of vascular supply, such as that caused by fibrocartilaginous embolisation. Clinical spinal cord injury (SCI) most commonly results from a combination of compression and contusion, for instance the injury caused by vertebral fracture-luxation or resulting from extrusion of the nucleus of an intervertebral disc. From a clinician's viewpoint, it is important to attempt to estimate the 'proportion' of damage resulting from each of these components, since it provides a means realistically to estimate the likely effect of surgical intervention. Studies in many species have suggested that the severity of injury is largely determined at the instant of the injury, especially in those in which contusion predominates.
机译：脊髓可以通过三个主要的病理机制造成伤害：i）挫伤，其中脊髓的快速开/关变形（类似于锤击吹出的结果）; II）压缩，其中脊髓经历持续变形;而且，III）直接损害血管供应，例如由纤维纤维栓塞引起的。临床脊髓损伤（SCI）最常见的是压缩和挫伤的组合，例如由椎骨骨折 - 逃避引起的损伤或由椎间盘核挤出引起的损伤。从临床医生的观点出发，以试图估计损害的“比例”从每个这些组分的所得的，因为它提供了一种手段现实估计手术干预的可能的效果是重要的。许多物种的研究表明，损伤的严重程度在很大程度上在损伤的瞬间确定，特别是在挫伤占占据罪的人中。

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