• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics >DART MS Analysis of Urushiol Oil (Poison Ivy) in Light Aliphatic Oil (WD 40) Causing Accidental Pediatric Allergic Contact Dermatitis (ACD)
【24h】

DART MS Analysis of Urushiol Oil (Poison Ivy) in Light Aliphatic Oil (WD 40) Causing Accidental Pediatric Allergic Contact Dermatitis (ACD)

机译：尿精油（毒药常春藤）在轻脂族油（WD 40）中的毛发油（毒镜）分析，导致意外小儿过敏性接触皮炎（ACD）

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Severe pediatric allergic contact dermatitis (ACD) was observed in some children playing near household vegetation. The dermatitis was caused by urushiol oil in poison ivy. However, certain cases exhibited severe dermatitis. This dermatitis appeared to be intensified in a subgroup of children whose clothing had been exposed to a light household oil prior to exposure. We conjectured that the light oil was simply dissolving the urushiol rather than chemically reacting with it. We found that the behavior of the urushiol in light oil could be visually simulated using Rhodamine 6g dye from a red permanent marker. This dissolution of the urushiol, which is a 1, 2 di-hydroxy 3 alkyl benzene, reacted as an enhanced delivery system through clothing, resulting in unusually severe reactions after the exposure to poison ivy. This study was prompted by observations of infrequent but unusually severe reactions in certain accidentally exposed children. We surmised that preliminary exposure to light aliphatic oils like WD-40, perhaps from toys or sports equipment was dissolving and transporting the urushiol through the clothing to increase skin contact. This resulted in severe dermatitis. DART mass spectrometry was used to surface desorb the analytes. The mass spectra clearly showed the irritant was urushiol, and not a chemical derivative. Urushiols are actually a class of catechols that feature a benzene diol with hydrocarbon tails which may vary slightly between samples.
机译：在一些孩子在邻近家庭植被的一些孩子中观察到严重的小儿过敏接触皮炎（ACD）。皮肤病是由毒液常春藤的尿精油引起的。然而，某些情况表现出严重的皮炎。这种皮炎似乎在儿童的亚组中加剧，其服装在暴露前暴露于轻质家用油。我们劝导轻油简单地溶解尿道，而不是化学反应。我们发现，可以使用来自红色永久性标记的罗丹明6g染料在视觉上模拟轻油中的尿精子的行为。这种脲硫醇的溶解是1,2二羟基3烷基苯，通过衣服作为增强的输送系统反应，导致暴露于毒物常春藤后异常严重的反应。通过观察缺乏频繁但在某些意外暴露的儿童中的异常严重反应促进了这项研究。我们抑制了初步暴露于像WD-40这样的轻脂族油，也许来自玩具或运动器材正在溶解并将毛细血管通过衣服运送以增加皮肤接触。这导致严重的皮炎。 DART质谱法用于表面解吸分析物。质谱清楚地表明刺激物是尿道，而不是化学衍生物。尿道实际上是一类特征，其具有苯二醇，碳氢化合物尾巴可以在样品之间略微变化。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号