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首页> 外文会议>American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics >Quantitative proteomic mapping of gingival crevicular fluid from dogs progressing from mild gingivitis to periodontitis
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Quantitative proteomic mapping of gingival crevicular fluid from dogs progressing from mild gingivitis to periodontitis

机译：从轻度牙龈炎从轻度牙龈炎到牙周炎的狗的定量蛋白质组学映射

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From GCF we have identified 1,071 canine proteins by two or more peptides at a 1 % false discovery rate; 327 (31 %) of these proteins were identified in all five teeth over time. In comparison to mild gingivitis 930 proteins were identified to be more abundant in severe gingivitis, and 460 were more abundant in mild periodontitis when compared to severe gingivitis. 76 of these proteins were observed to have a mean ≥2-fold increase in abundance in periodontitis in comparison to severe gingivitis.
机译：来自GCF，我们通过两个或更多个肽以1％的假发现率鉴定了1,071个犬蛋白;随着时间的推移，在所有五颗牙齿中鉴定了327（31％）这些蛋白质。与温和的牙龈炎930蛋白相比，鉴定在严重的牙龈炎中更丰富的蛋白质，与严重的牙龈炎相比，460次温和的牙周炎中更丰富。与严重的牙龈炎相比，观察到这些蛋白质中的76种牙周炎的平均值≥2倍。

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