首页> 外文会议>American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics >Mass Spectrometric Detection of Local Anesthetics Masking Prohibited Practice of Inducing Limb Soring in Walking Horses to Enhance Appeal
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Mass Spectrometric Detection of Local Anesthetics Masking Prohibited Practice of Inducing Limb Soring in Walking Horses to Enhance Appeal

机译:质谱检测局部麻醉剂掩盖禁止诱导肢体侵蚀行动马的侵蚀性提高吸引力

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The developed and validated LC-MS/MS method afforded the simultaneous identification of nine local anesthetic agents and also complied with criteria set up by regulatory agencies. The scheduled MRMs and the two transitions monitored for each compound offered adequate sensitivity and reliable confirmation of identity. The assay was successfully applied for analyzing real swab samples obtained from inspectors. In positive samples, lidocaine and/or benzocaine were detected, which are active ingredients in a number of common, commercially available and popular over-the-counter drug formulations (Study supported by FAST, Inc., and TWSHO; both Shelbyville, TN).
机译:开发和验证的LC-MS / MS方法提供了九个局部麻醉剂的同时鉴定,并遵守法规机构建立的标准。预定的MRM和每个化合物监测的两个过渡都提供了足够的灵敏度和可靠的身份确认。成功应用测定以分析从检查员获得的真实拭子样品。在阳性样品中,检测Lidocaine和/或苯并催化,其在许多常见,可商购和流行的过度反击药物制剂中是活性成分(由Fast,Inc。和Twsho支持的研究;谢尔比维尔,TN) 。

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