UHPLC-MS-MS with Fast Precursor Ion and Neutral Loss Scanning and Glutathione Trapping for Detecting Reactive Metabolites of Glabridin, an Isoflavan from Licorice

机译：UHPLC-MS-MS具有快速前体离子和中性损失扫描和谷胱甘肽诱捕，用于检测甘草的异黄酮的反应性代谢物，来自甘草的异黄酮

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Mixtures of GSH and labeled GSH during UHPLC-MS-MS facilitated the unambiguous detection of GSH conjugates of electrophilic metabolites. Polarity switching with precursor ion and constant neutralloss MS- MS scanning permitted the detection of more GSH conjugates than before. Three GSH conjugates of glabridin were detected, and epoxide intermediates were implicated.

机译：UHPLC-MS-MS期间GSH和标记GSH的混合物促进了亲电子代谢物的GSH缀合物的明确检测。具有前体离子和恒定的中性标量的极性切换MS-MS MS-MS扫描比以前检测更多GSH共轭。检测到甘草蛋白的三种GSH缀合物，并牵连环氧化物中间体。

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《American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics》|2013年||共1页
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Ke Huang; Richard B. van Breemen;
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机译：UHPLC-MS-MS具有快速前体离子和中性损失扫描和谷胱甘肽，用于检测来自甘草的异黄酮的无反应性代谢物
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UHPLC-MS-MS with Fast Precursor Ion and Neutral Loss Scanning and Glutathione Trapping for Detecting Reactive Metabolites of Glabridin, an Isoflavan from Licorice

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