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Immunological basis of M13 phage vaccines: an effective vaccine design tested in a mouse model of Alzheimer's disease

机译：M13噬菌体疫苗的免疫基础：在阿尔茨海默病的小鼠模型中测试了有效的疫苗设计

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When mice were immunized up. with M13 phage without adjuvant, specific IgG was produced in primary response under MyD88-signaling. Consistently, Ap42-reactive IgG2b was elicited by the Ap42-fiber-mi-motope-displaying phage clone (B6-C15), suggesting the promising feature of M13 phage for vaccine design.

机译：当小鼠被免疫的时候。使用M13噬菌体而不具有佐剂，在MyD88信号传导下以初级反应产生特异性IgG。始终如一地，AP42-纤维 - MI-MOTOPE噬菌体克隆（B6-C15）引发了AP42-反应性IgG2B，表明M13噬菌体疫苗设计的有希望的特征。

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《Japanese peptide symposium》|2011年||共1页
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作者
Shuhei Hashiguchi; Yuya Yamaguchi; Haruna Tahara;
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中图分类肽类;
关键词
Mimotope; Bacteriophage; Innate immunity; Vaccine; Phage-display;

机译：Mimotope;噬菌体;先天免疫;疫苗;噬菌体展示;

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专利

1. Immunological basis of M13 phage vaccine: Regulation under MyD88 and TLR9 signaling. [J] . Hashiguchi S, Yamaguchi Y, Takeuchi O, Biochemical and Biophysical Research Communications . 2010,第1期

机译：M13噬菌体疫苗的免疫学基础：MyD88和TLR9信号转导下的调控。
2. Immunological basis of M13 phage vaccine: Regulation under MyD88 and TLR9 signaling. [J] . Hashiguchi S, Yamaguchi Y, Takeuchi O, Biochemical and Biophysical Research Communications . 2010,第1期

机译：M13噬菌体疫苗的免疫学基础：MyD88和TLR9信号转导下的调控。
3. DNA vaccines effective in mouse model of Alzheimer's disease [J] . The Pharmaceutical Journal Group The pharmaceutical journal . 2006,第7405期

机译：对阿尔茨海默氏病小鼠模型有效的DNA疫苗
4. Immunological basis of M13 phage vaccines: an effective vaccine design tested in a mouse model of Alzheimer's disease [C] . Shuhei Hashiguchi, Yuya Yamaguchi, Haruna Tahara Japanese peptide symposium . 2011

机译：M13噬菌体疫苗的免疫基础：在阿尔茨海默病的小鼠模型中测试了有效的疫苗设计
5. Immunological Benefits of a Novel polycaprolactone-polyorthoester-based Therapeutic Vaccine in a Mouse Model of Glioma. [D] . Grinnen, Karen Lynn. 2014

机译：新型基于聚己内酯-聚原酸酯的治疗性胶质瘤小鼠模型的免疫学益处。
6. Phage-Displayed T-Cell Epitope Grafted into Immunoglobulin Heavy-Chain Complementarity-Determining Regions: an Effective Vaccine Design Tested in Murine Cysticercosis [O] . Karen Manoutcharian, Luis Ignacio Terrazas, Goar Gevorkian, 1999

机译：噬菌体展示的T细胞表位嫁接到免疫球蛋白重链互补决定区：在鼠类囊尾Test病中测试的有效疫苗设计。
7. Phage-Displayed T-Cell Epitope Grafted into Immunoglobulin Heavy-Chain Complementarity-Determining Regions: an Effective Vaccine Design Tested in Murine Cysticercosis [O] . Karen Manoutcharian, Luis Ignacio Terrazas, Goar Gevorkian, 1999

机译：噬菌体展示的T细胞表位接枝到免疫球蛋白重链互补 - 测定区域：在鼠囊霉菌中测试有效的疫苗设计
8. Development of Safe, Effective Vaccines for Dengue Virus Disease by RecombinantBaculovirus. Subtitle: Development of Safe, Effective Vaccines for Dengue Disease Utilizing Viral Envelope and NSI Glycoproteins Expressed by Recombinant Baculovirus [R] . Lai, C. J. 1991

机译：利用重组杆状病毒开发安全有效的登革病毒疫苗。副标题：利用重组杆状病毒表达的病毒包膜和NsI糖蛋白开发安全有效的登革病疫苗

Immunological basis of M13 phage vaccines: an effective vaccine design tested in a mouse model of Alzheimer's disease

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