• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>International Gastric Cancer Congress >Erih Genes and Gastric Cancer
【24h】

Erih Genes and Gastric Cancer

机译：ERIH基因和胃癌

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Erih genes which are peripheral clock genes (so-called watch genes) were discovered from Bmal2/CLIF/ARNTL2 genes using yeast two hybrid methods. Erih genes have roles as downstream of Bmal2/CLIF/ARNTL2 genes during circadian rhythm. Circadian rhythm is important to cancer treatment.First, small interfering RNAs were designed against Erih genes, and then added to cultured cells and incubated for a while. Second, the RNAs were extracted from the cultured cells, and then examined with microarray.After the addition of small interfering RNA against Erih genes, the expressions of several genes which have immunological roles were changed. These genes' products may have effects on gastric cancer treatment.The control of Erih genes may be useful to gastric cancer treatment.
机译：使用酵母两种杂化方法从BMA12 / CLIF / ARNTL2基因发现是外周钟学基因（所谓的手表基因）的ERIH基因。 ERIH基因在昼夜节律期间具有作为BMA12 / CLIF / ARNTL2基因下游的作用。 昼夜节律对癌症治疗至关重要。首先，小型干涉RNA针对ERIH基因设计，然后加入培养细胞并孵育一段时间。 其次，从培养的细胞中提取RNA，然后用微阵列检查。加入小干扰RNA对ERIH基因的，改变了几种具有免疫作用的基因的表达。 这些基因的产品可能对胃癌治疗产生影响。ERIH基因的控制可能对胃癌治疗有用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号