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Mushrooms for Nerve Health-Our Research Findings

机译：神经健康的蘑菇 - 我们的研究结果

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Culinary and medicinal mushrooms are renowned for their health benefits on the various systems in the human body that can contribute to wellness and quality of life. As we age, we are prone to a number of life debilitating diseases including nerve related diseases. Further, dementia and Alzheimer's diseases are the most devastating. In traditional Chinese and Japanese therapy, Hericium erinaceus has been reported to help stimulate neurite outgrowth which may help reduce or delay on set of dementia. In this study, other culinary and medicinal mushrooms including the edible Pleurotus giganteus and nonedible Lignosus rhinocerus and Ganoderma neojaponicum were investigated for benefits to the nervous system. The extracts of fruiting bodies, sclerotia or mycelium of the selected mushrooms stimulated neurite outgrowth of PC 12 cells. All three mushrooms had varying degrees of stimulatory activities on neurite outgrowth. The activities of L. Rhinocerus, a wild medicinal mushroom were comparable or significantly better at low concentrations when compared to aqueous and ethanol extracts of H. Erinaceus extracts and nerve growth factor (NGF). Aqueous extract of all three mushrooms studied contained bioactive molecules that mimic NGF that is responsible for neurite stimulation activity. The extracts were not toxic to cell lines used in this study. Further, the extracts had genoprotective and anti-inflammatory activities that may contribute to nerve health, too.
机译：烹饪和药用蘑菇在人体中的各种系统中荣获他们的健康益处，可以促进生命的健康和质量。随着我们的年龄，我们倾向于一些衰弱的衰弱疾病，包括神经相关疾病。此外，痴呆和阿尔茨海默氏病是最毁灭性的。在繁体中文和日本治疗中，据报道，赫内斯·埃里纳斯·赫内斯氏植物有助于刺激神经突的遗传，这可能有助于减少或延迟痴呆症。在这项研究中，研究了包括可食用的胸膜牙龈和非可爱的木质素犀牛和无味性木质素犀牛和Ganoderma Neojaponicum的其他烹饪和药用蘑菇用于对神经系统有益。所选蘑菇的果实，巩膜或菌丝体的萃取液刺激了PC 12细胞的神经突生长。所有三个蘑菇都有不同程度的神经沸石过多的刺激活动。 L.犀牛的活性，野生药用蘑菇的活动与H.Suinaceus提取物和神经生长因子（NGF）的水性和乙醇提取物相比，在低浓度下与低浓度相当或明显更好。研究的所有三种蘑菇的水质提取物含有对MIMIC的生物活性分子，其负责神经突刺激活性。提取物对本研究中使用的细胞系无毒。此外，提取物具有可能有助于神经健康的基因保护和抗炎活动。

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