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首页> 外文会议>World Forum on Advanced Materials >Superparamagnetic Nanocomposites of Poly(vinyl alcohol-graft-acrylonitrile) as Carrier for Magnetically Assisted Release of Ciprofloxacin
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Superparamagnetic Nanocomposites of Poly(vinyl alcohol-graft-acrylonitrile) as Carrier for Magnetically Assisted Release of Ciprofloxacin

机译：聚（乙烯醇 - 移植物 - 丙烯腈）的超顺磁纳米复合材料作为环丙沙星磁辅助释放的载体

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In the present study also a superparamagnetic nanocomposite of Poly (vinyl- alcohol-g-acrylonitrile) has been designed by homogeneous impregnation of iron oxide nanoparticles into the graft polymer matrix. The so prepared nanocomposite was characterized by FT-IR, TEM and XRD techniques and studied for water sorption behavior and magnetization properties. The superparamagnetic nanocomposite was loaded with an antibiotic drug, ciprofloxacin (CFx), and its release behavior was investigated under varying experimental conditions such as chemical composition of the matrix, pH of the release media, applied magnetic field and percent loading of the drug. The drug transport mechanism was also analyzed using Ficks power law. The drug loaded magnetic nanocomposite was also studied for antibacterial and in-vitro blood compatible properties.
机译：在本研究中，通过均匀浸渍氧化铁纳米颗粒进入接枝聚合物基质，设计了聚（乙烯基 - 醇-G-丙烯腈）的超顺磁性纳米复合材料。通过FT-IR，TEM和XRD技术表征如此制备的纳米复合材料，并研究了水吸附行为和磁化性能。将超顺磁性纳米复合材料加载抗生素药物，环丙沙星（CFX），并在不同的实验条件下研究其释放行为，例如基质的化学成分，释放介质的pH，施加的磁场和药物的百分比。还使用Ficks Power Law分析了药物传输机制。还研究了药物负载的磁性纳米复合物用于抗菌和体外血液相容性质。

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