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RELATIONSHIPS BETWEEN THE O-POLYSACCHARIDES OF ESCHERICHIA COLI AND OTHER ENTERIC BACTERIA

机译:大肠杆菌和其他肠溶细菌的O-多糖之间的关系

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The O-specific polysaccharide chain of the lipopolysaccharide called the O-antigen is an important component of the outer membrane of the cell wall of gram-negative bacteria. Being exposed to the bacterial cell surface, the O-antigen is subject to intense selection by the host immune system and bacteriophages giving rise to diverse O-antigen forms and providing the basis for typing of bacteria. The O-antigen forms of many bacteria are unique, whereas some are structurally and genetically related to others. Multiple genetic mechanisms of diversification of the O-antigen forms, such as lateral gene transfer and mutations, have been reported.
机译:称为O-抗原的脂多糖的特异性多糖链是革兰氏阴性细菌的细胞壁外膜的重要组成部分。暴露于细菌细胞表面,O-抗原受到宿主免疫系统和噬菌体的强烈选择,产生不同的O-抗原形式并为键入细菌提供基础。许多细菌的O-抗原形式是独特的,而有些细菌在结构上和遗传上与他人有关。据报道,据报道了o-抗原形式的多种多样化的多种遗传机制,例如横向基因转移和突变。

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