首页> 外文会议>International Carbohydrate Symposium >A NOVEL SYNTHETIC APPROACH TOWARD DIVERSE p-GLYCEROGLYCOLIPIDS BASED ON A NEIGHBORING FREE 1,2-trans-SELECTIVE GLYCOSYLATION
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A NOVEL SYNTHETIC APPROACH TOWARD DIVERSE p-GLYCEROGLYCOLIPIDS BASED ON A NEIGHBORING FREE 1,2-trans-SELECTIVE GLYCOSYLATION

机译:基于相邻自由1,2-反式选择性糖基化的一种新型P-甘油基哌普体的一种新型合成方法

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The stereoselective construction of glycosidic bond is of the greatest importance to achieve the efficient synthesis of glycan molecules. Generally, to obtain 1,2-trans-selectivity the neighboring participation of acyl group has been most widely used. However, the method is not always suitable for the synthesis of ester substituted glycoconjugates, which are represented by ss-glycerogiycolipids. Recently, we have developed a neighboring participation independent 1,2-trans-selective glycosylation method[1]. We herein describe the newly developed glycosylation reaction and its application to the synthesis of ss-glyceroglycolipids.
机译:糖苷键的立体选择性构建是达到甘草分子的有效合成的重要性。通常,为了获得1,2-反式选择性,酰基的相邻参与最广泛地使用。然而,该方法并不总是适用于合成酯取代的糖缀合物,其由SS-甘油哌妥脂代表。最近,我们开发了邻近参与的独立1,2-反式选择性糖基化方法[1]。我们在本文中描述了新开发的糖基化反应及其在合成SS-甘油基哌妥啶的应用。

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