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Bioactive cubitane diterpenoids from a Colombian gorgonian species of the genus Eunicea

机译：来自欧盟属的哥伦比亚Gorgonian物种的生物活性立方体二萜类化合物

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Two new diterpenes having the rare cubitane skeleton were isolated from a southwestern Caribbean gorgonian coral of the genus Eunicea. The structures of the new metabolites, as well as those of three known cubitanes were elucidated by extensive spectroscopic analysis. One compound showed significant in vitro cytotoxic activity against a National Cancer Institute (NCI) panel of cancer cell lines, whereas the remaining metabolites were shown to exert mild antitubercular and antimalarial activities against the pathogenic microbes Mycobacterium tuberculosis and Plasmodium falciparum.

机译：从西南加勒比海西南加勒比海哥伦亚珊瑚中分离出具有罕见的立方体骨架的两种新的二萜。通过广泛的光谱分析阐明了新代谢物的结构以及三个已知的封壳的结构。一种化合物对全国癌症研究所（NCI）小组进行了显着的体外细胞毒性活性，而剩余的代谢物被证明对致病微生物结核分枝杆菌和疟原虫的致病性微生物和疟原虫进行抗疟疾和抗疟疾活性。

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《IUPAC World Congress on Chemistry》|2015年||共9页
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Xiaomei Wei; Karinel Nieves; Abimael D. Rodriguez;
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中图分类应用化学;
关键词
anticancer activity; antimalarial activity; antitubercular activity; Caribbean gorgonian; Eunicea sp.; infectious deseases; isolation; marine chemistry; natural products; physicochemical characterization of cubitane diterpenes; structures.;

机译：抗癌活动;抗疟活动;抗真菌活动;Caribbean Gorgonian;eunicea sp。;传染性休眠;隔离;海洋化学;天然产品;立方体的物理化学表征;结构。;

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1. Bioactive cubitane diterpenoids from a Colombian gorgonian species of the genus Eunicea [J] . Wei X., Nieves K., Rodríguez A.D. Pure and Applied Chemistry . 2012,第9期

机译：来自Eunicea属哥伦比亚高哥氏菌物种的生物活性cubitane二萜
2. Dolabellane-type diterpenoids with antiprotozoan activity from a southwestern Caribbean gorgonian octocoral of the genus Eunicea. [J] . Wei X, Rodriguez AD, Baran P, Journal of natural products . 2010,第5期

机译：具有反原生动物活性的多拉姆兰型二萜类化合物，来自Eunicea属的西南加勒比海戈尔肯八角。
3. Antiplasmodial cembradiene diterpenoids from a Southwestern Caribbean gorgonian octocoral of the genus Eunicea [J] . Wei XM, Rodriguez AD, Baran P, Tetrahedron . 2004,第51期

机译：来自Eunecea属的西南加勒比海高哥氏八叶虫的抗疟原虫二萜
4. Bioactive cubitane diterpenoids from a Colombian gorgonian species of the genus Eunicea [C] . Xiaomei Wei, Karinel Nieves, Abimael D. Rodriguez IUPAC World Congress on Chemistry . 2015

机译：来自欧盟属的哥伦比亚Gorgonian物种的生物活性立方体二萜类化合物
5. Bioactive terpene production associated with Caribbean gorgonians from the genera Pseudopterogorgia and Eunicea: Discovery of a sustainable production method. [D] . Newberger, Nealie C. 2006

机译：与假鳞翅目和Eunicea属的加勒比海鳄相关的生物活性萜烯生产：发现一种可持续的生产方法。
6. Dolabellane-Type Diterpenoids with Antiprotozoan Activity from a Southwestern Caribbean Gorgonian Octocoral of the Genus Eunicea [O] . Xiaomei Wei, Abimael D. Rodríguez, Peter Baran, -1

机译：Dolabellane型二萜抗原生动物与从活动属Eunicea的西南加勒比海柳珊瑚Octocoral
7. Bioactive (3Z,5E)-11,20-Epoxybriara-3,5-dien-7,18-olide Diterpenoids from the South China Sea Gorgonian Dichotella gemmacea [O] . Li, Cui, La, Ming-Ping, Sun, Ping, 2017

机译：来自中国南海Gorgonian Dichotella gemmacea的生物活性（3Z，5E）-11,20-环氧嘧啶-3,5-二烯-7,18-醇二萜类化合物

Bioactive cubitane diterpenoids from a Colombian gorgonian species of the genus Eunicea

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