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Patient-Specific Bile Flow Simulation to Evaluate Cholecystectomy Outcome

机译：患者特异性胆汁流模拟，以评估胆囊切除术结果

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Gallbladder disease has one of the leading positions by patients’number in the World.About 16% of the adult population is suffering now from this disease.Cholecystectomy is believed to be a general surgical method of the gallbladder disease treatment,but the success rate is quite low because the surgeons do not take into account the patient-specific features during the treatment and cannot predict operation results.The main purpose of the paper is to create a computational tool for numerical evaluation of cholecystectomy outcome compared with healthy state and current pathological state based on the patient-specific patients’data.The patient-specific features of the biliary tree were studied by 1-way FSI bile flow simulation.The extra-hepatic biliary tree geometries were extracted from MRI and after that imported to ANS YS CFX for the subsequent fluid dynamics analysis.lt was revealed that in the pathology state,velocities were found to have lower magnitude while the pressures were higher.The patient-specific features have a dramatic influence on the bile flow patterns.Cholecystectomy leads to the decrease of bile flow rate in the extra-hepatic biliary tree.The proposed computational approach can be applied to medical practice to evaluate the circumstances of surgical interventions.
机译：胆囊病有一个患者在世界上的领先地位之一。从这个疾病中，16％的成年人口正在患有患有疾病。被认为是胆囊病治疗的一般外科手术方法，但成功率是相当低，因为外科医生在治疗过程中没有考虑到患者特异性，并且不能预测操作结果。本文的主要目的是为与健康状态和当前病理状态相比，胆囊切除术成果的数值评估的计算工具基于患者特异性患者的胆汁患者的特异性特征是通过1向FSI胆汁流模拟研究了胆汁树的特异性。从MRI提取肝脏胆树胆树几何形状，然后在进口到ANS YS CFX之后随后的流体动力学分析显示，在病理状态下，发现速度较低，而压力是HIG患者特异性特征对胆汁流动模式具有显着影响。颅骨切除术导致肝脏胆汁胆树中的胆汁流速降低。建议的计算方法可以应用于医学实践以评估外科手术的情况干预措施。

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