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P50 and P300 Event Related Potentials in Patients with Schizophrenia Recorded from High-Density EEG

机译:从高密度脑电图记录精神分裂症患者的P50和P300事件相关电位

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The main objectives of this study were to describe P50 and P300 cortical topography in patients with schizophrenia and to define a robust methodology of signal quantification using high density EEG. Within a clinical trial in which patients with schizophrenia and auditory verbal hallucinations were submitted to 10 days rTMS treatment, P50 and P300 were investigated as possible neurophysiological measurements to assess treatment effectiveness together with psychometric scales like Psychotic symptom rating scale (PSY-RATS), depression, anxiety and stress scale (DASS) and Quality of Life scale (QoL). Here we describe the technique of collecting P50 and P300 using high-density EEG and we reproduce the preliminary data of P300 in one healthy subject and P50 in two patients and two healthy subjects.
机译:本研究的主要目标是描述精神分裂症患者的P50和P300皮质地形,并使用高密度EEG定义信号量化的鲁棒方法。在一个临床试验中,将患有精神分裂症和听觉伐木幻觉的患者提交10天的RTMS治疗,P50和P300作为可能的神经生理测量,以评估治疗效果以及精神病症状评级规模(PSY-RAT),抑郁症等心理尺度,焦虑和压力规模(DASS)和生活质量(QOL)。在这里,我们描述了使用高密度脑电图收集P50和P300的技术,并在两名患者和两个健康受试者中再现P300的P300的初步数据和P50。

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