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Dynamic Simulation of Sexual Partner Networks: which Network Properties are Important in Sexually Transmitted Disease (STD) Epidemiology?

机译:性伴侣网络的动态模拟:哪种网络属性在性传播疾病(STD)流行病学中是重要的?

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Conventional deterministic models of infection spread through populationsaggregate individuals into compartments and study the dynamics of the re-sulting simplified system (Anderson and May 1991, Hethcote and Van Ark1992). In this paper we explore whether knowledge of contact networks atan individual level can add to our epidemiological understanding in the par-ticular setting of STDs. In the case of STDs the limited number and welldefined nature of sexual contacts between people allows the description ofthe networks along which an STD can spread (Klovdahl et al. 1992, 1994).To this end a simple model describing the sexual behaviour of individuals isdeveloped which generates sexual partner networks. The spread of a sexu-ally transmitted disease (STD) through the population is simulated, and thecharacteristics of the network are related to the resultant spread of the STD.The model constructed contains many assumptions about the mechanismscontrolling the sexual partnership formation behaviour, which are varied togenerate a large range of possible networks. A central aim of this work is thedevelopment of the model as a tool to assist in the analysis of behaviouraldata. From simulations the parameters which are most influential in STDepidemiology can be identified. Samples can be taken from this network in away which mirrors methods of sampling used in behavioural research.
机译:传统的确定性型号的感染模型通过人群传播的人群进入隔间,研究了重新淘汰简化系统的动态(Anderson和1991年5月,Hethcote和Van Ark1992)。在本文中,我们探讨了对个人级别的联系网络知识是否可以在STD的分析环境中增加我们的流行病学理解。在STDS的情况下,人们之间的性接触的有限数量和良好的性质允许STD可以传播的网络的描述(Klovdahl等,1992,1994)。这是一个简单的模型,描述了个人的性行为是isdeveloped的性别产生性伴侣网络。通过人口一个sexu烯丙基传播疾病(STD)的传播进行模拟,并且网络的thecharacteristics涉及构造的STD.The模型的所得扩散包含有关的许多假设的mechanismscontrolling性伙伴关系形成的行为,这是各种各样的一系列可能的网络。这项工作的核心目标是模型作为一种协助分析行为的工具。从模拟中可以识别在stdepidemiology中最具影响力的参数。可以从该网络中取出样品,以便在行为研究中镜像采样方法。

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