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ABERRATIONS INDUCED IN CHROMOSOME 1,2 AND Y OF HUMAN LYMPHOCYTES BY THREE TYPES OF RADIATION OF DIFFERENT LET VALUE AS DETECTED BY FISH

机译:在染色体1,2和γ中诱导的畸变,通过鱼类检测到的不同诱导的三种辐射辐射

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Fluorescence in situ hybridisation was used to determine the efficiency of the induction of aberrations in chromosomes 1, 2 and Y of human lymphocytes by y-rays, fast neutrons of mean energy of 7 MeV and accelerated nitrogen ions. The frequency and the spectrum of aberration types induced by these three types of radiation were different. Nitrogen ions induced the highest number of aberrations. The most frequent were chromosome fragments followed by centric rings. Neutrons and γ-rays induced most frequently translocations followed by dicentric chromosomes. Efficiency of neutrons in the induction of aberrations was higher in comparison with y-rays. Induction of aberrations by both y-rays and fast neutrons in Y chromosome was much less effective in comparison with chromosome 1. The low efficiency of these types of radiation in the induction of aberrations in Y chromosome is probably related to the lower content of DNA in this chromosome and to its higher content of hetero-chromatin.
机译:使用原位杂交的荧光用于通过Y射线测定人淋巴细胞的染色体1,2和Y中的畸变诱导的效率,快速中子为7meV和加速氮离子的平均能量。这三种辐射诱导的像差类型的频率和频谱不同。氮离子诱导最多的像差。最常见的是染色体片段,然后是中心环。中子和γ射线诱导最常见的易位,然后是Dicentric染色体。与Y射线相比,诱导像差诱导中子的效率。与染色体的γ射线和快节中子的诱导均匀效果较小。与染色体1相比,这些类型的辐射在Y染色体诱导中的低效率可能与DNA的较低含量有关该染色体和其含量较高的异染色质含量。

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