首页> 外文会议>NATO advanced research workshop on ocular radiation risk assessment in populations exposed to environmental radiation contamination >POSTERIOR SUBCAPSULAR CATARACT AND DRY EYE SYNDROME AFTER RADIATION EXPOSURE BY THE CHERNOBYL ACCIDENT
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POSTERIOR SUBCAPSULAR CATARACT AND DRY EYE SYNDROME AFTER RADIATION EXPOSURE BY THE CHERNOBYL ACCIDENT

机译:切尔诺贝利事故后辐射曝光后后亚片性白内障和干眼症综合征

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During the nuclear accident of Chernobyl in April 1986 numerous reactor workers and fire fighters were exposed to large doses of ionizing radiation. In addition to high ambient γ-ray exposures, these men suffered from a very inhomogenous contamination with fission products on their wet and insufficiently protective clothing, and a resulting severe exposure of the skin, predominantly with β-rays. 16 Chernobyl clean-up workers and 4 persons exposed during nuclear accidents at other nuclear installations were repeatedly examined between September 1991 and September 1996. The radiation exposures ranged from 0.35 to 9 Gy, according to data notified by GUS authorities. They were, in their general trend, confirmed by the determination of chromosome aberrations. The medical therapeutic measures were focused on orthopedic prosthetics and the treatment of chronic radiation dermatitis. Ophthalmological examinations included biomicroscopy of the anterior and ophthalmoscopy of the posterior eye segments. Quantitative assessment of ocular radiation damage, especially to the lens and the documentation of subsequent development of cataract was achieved by application of an electronic Scheimpflug camera system (Topcon SL-45, modified) that included image analysis for quantification of lens opacities. 2 patients had already undergone cataract extraction at first presentation, posterior subcapsular lens opacities were seen in 6 patients, 1 patient presented dense corticonuclear cataracts and pseudoexfoliation-like changes. 4 patients had chronic dry eye syndrome (reduced tear production in Schirmer test). Retinal radiation damages were not detected. No ocular radiation injuries were detected in 9 patients. Posterior subcapsular cataracts were found to be the predominant consequence of ocular radiation exposure in our patients. There is, at this point, no distinct correlation of ocular findings with the distribution and level of chronic cutaneous radiation damage or with the whole body doses.
机译:在1986年4月的切尔诺贝利的核事故中,许多反应堆工人和消防员暴露于大剂量的电离辐射。除了高环境γ射线暴露之外,这些男性还遭受了湿润和不充分的防护服的裂变产品的非常偏离污染,并且主要具有β射线的严重暴露。根据Gus当局通知的数据,在1991年9月和1996年9月期间,在1991年9月和9月间核对其他核设施期间暴露的核事故中的核事故清理工人和4名核对者的4人。根据Gus当局通知的数据,辐射曝光范围为0.35至9 GY。他们在普遍趋势中,通过测定染色体畸变来证实。医学治疗措施集中在骨科假肢和治疗慢性辐射皮炎。眼科检查包括后眼段的前胸腔和眼镜镜的生物显微镜。通过应用电子Scheimpflum相机系统(TOPCON SL-45,修改)来实现对眼睛辐射损伤的定量评估,特别是对白内障的后续发育的文献,包括用于量化透镜透明度的图像分析。 2例患者在第一次介绍时已经经历了白内障萃取,6例患者中,后亚面容晶状体不间断,1例患者呈现致密的皮质核核发性和伪挑选的变化。 4名患者患有慢性干眼症综合征(Schirmer测试中的撕裂产生)。未检测到视网膜辐射损坏。在9名患者中检测到任何眼部辐射损伤。发现后亚面脓性白内障是我们患者眼部辐射暴露的主要结果。此时,目前没有与慢性皮肤辐射损伤或全身剂量的分布和水平不同的相关性。

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