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Artificial Sub-Micron Diameter Silk Fibers Under Benign Processing Conditions by Two-fluid Electrospinning

机译:人造亚微米直径丝纤维在良性加工条件下双流体静电纺丝

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Silk fibroin has been investigated widely as a biomaterial for such applications as medical sutures and tissue engineering scaffolds. Recent advances in molecular biotechnology and protein engineering offer the capability to produce large quantities of silk and other polypeptide-based biopolymers. However, there remains to date no commercially feasible method for manufacturing synthetic fibers from such biopolymers such that they retain the excellent intrinsic properties, such as mechanical properties and biocompatibility, of natural silk fibers. Methods that mimic the natural spinning process employed by silkworms or other insects appear to be especially promising.
机译:已经广泛研究了丝素蛋白,作为这种应用的生物材料,如医疗缝合线和组织工程支架。分子生物技术和蛋白质工程的最新进展提供了产生大量丝绸和其他基于多肽的生物聚合物的能力。然而,迄今为止,没有用于制造来自这种生物聚合物的合成纤维的商业上可行的方法,使得它们保留了天然丝纤维的优异内在性质,例如机械性能和生物相容性。模拟蚕或其他昆虫采用的天然纺纱工艺的方法似乎特别有前途。

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