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首页> 外文会议>NATO Advanced Research Workshop on Assessment and Management of Environmental Risks: Methods and Applications in Eastern European and Developing Countries >DRINKING WATER CONTAMINATION BY NITRATE AND LOW BIRTH WEIGHT RISK IN RURAL POPULATION
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DRINKING WATER CONTAMINATION BY NITRATE AND LOW BIRTH WEIGHT RISK IN RURAL POPULATION

机译：农村人口硝酸盐和低出生体重风险饮用水污染

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The aim of our study was to assess whether high nitrate levels in drinking water, consumed during pregnancy, increased the risk of low birth weight. The population-based case-control study was comprised of all low birth weight newborns, registered in 1996 in rural districts. Controls were randomly selected from the total birth cohort (1,057). We interviewed women in person about their sociodemographic characteristics, habits, reproductive and medical history. Total nitrate concentration in drinking water was used as an index of mother's exposure to nitrate. We compared low birth weight newborns (41 cases) with normal weight newborns (435 controls) and employed multivariate logistic regression to adjust for potential variable effects of the selected low birth weight risk factors. The risk of delivering a low birth weight newborn increased with increasing exposure to drinking water nitrate from 1.15, 95 percent CI=0.37-3.33 (for levels not exceeding 45 mg per liter) to 7.25, 95 percent CI=2.80-18.57 for levels higher than the safety level. After adjustment for selected low birth weight risk factors, the excess risk remained associated with several variables. The factors that significantly increased the risk of low birth weight were negative emotions, hypertonic disease, previous premature birth, and nitrate level in drinking water higher than 45mg per liter. The study results indicated that prenatal exposure to nitrate concentrations, exceeding drinking water safety levels may have increased low birth weight risk in agricultural areas.
机译：我们的研究目的是评估饮用水中的高硝酸盐水平是否在怀孕期间消耗，增加出生体重低的风险。基于人口的案例对照研究由所有低出生体重新生儿组成，1996年在农村地区注册。对照组是从总出生队列（1,057）中的。我们采访了女性对他们的社会渗塑特征，习惯，生殖和病史的人。饮用水中的总硝酸盐浓度被用作母亲暴露于硝酸盐的指标。我们将低出生体重新生儿（41例）与正常重量的新生儿（435个对照）进行比较，并采用多变量逻辑回归来调整所选择的低出生体重风险因素的潜在变量效应。随着饮用水硝酸盐从1.15，95％CI = 0.37-333（每升45毫克的水平）的饮用水硝酸盐的饮用水硝酸盐的越来越低，95％，CI = 2.80-18.57的水平增加比安全水平。在调整选定的低出生体重风险因素后，过度的风险与几个变量相关。显着增加出生体重风险的因素是负面情绪，高渗疾病，先前的早产，饮用水中的硝酸盐水平高于每升45mg。研究结果表明，产前暴露于硝酸盐浓度，超过饮用水安全水平可能会增加农业区域的低出生体重风险。

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