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Study on Dual-Energy X-ray Computed Tomography using Synchrotron Radiation

机译:使用同步辐射的双能X射线计算机断层扫描研究

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The electron density is one of the most important elements for the treatment planning in the radiotherapy, because this information is used for the range estimation of the heavy-ion beam. In order to measure more precise electron density, we have developed the dual-energy x-ray CT system using synchrotron radiation. The x-ray detector consists of 256 × 96 scintillator-array. It can take more than a hundred projection images per second. The response of the detector to x-rays was proved to be linear up to at least 1013 photon/pixel. The experiments were carried out using two monochromatic x-rays of 40 keV and 70 keV at the beam-line BL20B2 of SPring-8. As the results from samples of water, ethanol and solutions of dipotassium hydrogenphosphate with five concentrations, the electron densities measured in the dual-energy x-ray CT method were in agreement with the theoretical values by about ± 1%. This is almost the same level as that achieved by the one-dimensional CT system we developed previously. In addition, a sample of kidney of a pig fixed by formalin neutral buffer solution was used to distinguish the tissues in the CT images based on the electron density and the effective atomic number that was additionally obtained in the dual-energy x-ray CT. It suggested that renal pelvis was enriched with adipose tissue, and it was difficult to distinguish renal cortex and renal medulla.
机译:电子密度是放射疗法治疗计划中最重要的元素之一,因为该信息用于重型离子束的范围估计。为了测量更精确的电子密度,我们开发了使用同步辐射的双能X射线CT系统。 X射线探测器由256×96闪烁体阵列组成。它每秒可以花费超过一百个投影图像。证明了检测器对X射线的响应是直到至少1013光子/像素的线性。在弹簧-8的光束线BL20B2处使用两个40keV和70keV的两个单色X射线进行实验。作为水,乙醇和氢磷酸二磷酸溶液的结果,用五种浓度,在双能X射线CT方法中测量的电子密度与理论值一致约±1%。这与我们之前开发的一维CT系统实现的级别几乎是相同的。此外,使用福尔马林中性缓冲溶液固定的猪的肾脏样品基于在双能X射线CT中另外获得的电子密度和有效原子数区分CT图像中的组织。它表明肾盂富含脂肪组织,难以区分肾皮质和肾髓质。

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