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首页> 外文会议>Society of Photo-Optical Instrumentation Engineers Proceedings >A Pilot Study on Less-Stressful Bowel Preparation for Virtual Colonoscopy Screening with Follow-up Biopsy by Optical Colonoscopy
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A Pilot Study on Less-Stressful Bowel Preparation for Virtual Colonoscopy Screening with Follow-up Biopsy by Optical Colonoscopy

机译：光学结肠镜检查随访活组织检查筛选虚拟结肠镜检查较低压力肠道准备的试验研究

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Objective: To investigate a less stressful bowel preparation for polyp screening by virtual colonoscopy (VC) with follow-up biopsy on the positive findings by optical colonoscopy (OC). Materials and Methods: Fifty-eight volunteers of age older than 40 -- receiving low-residue diet and laxatives of magnesium citrate, bisacodyl tablets and suppository -- were divided into three groups. In Group I, 16 volunteers took three 40cc oral doses of MD-Gastroview with the three meals respectively, the day prior to VC procedure. In Group II, 18 volunteers ingested barium sulfate suspension (2% w/v, 250 cc/dose) at bedtime and in the next day morning of VC. In Group III, 24 volunteers received 60 cc of MD-Gastroview at bedtime and in the next day morning of VC. Following colon inflation with CO2, computer tomography (CT) abdominal images were acquired by a standard single-slice detector-band VC protocol, i.e., 5 mm collimation, 1 mm reconstruction, 1.5-2.0:1.0 pitch, 120 kVp and 100-150 mA. The CT density of the tagged residual fluid was measured. An image segmentation algorithm was applied to remove electronically the residue fluid. Results: The average fluid density was 97 HU for Group I, 221 HU for Group II2, and 599 HU for Group III. These three groups’ density means are significantly different (p < 0.001 one-way ANOVA). After the electronic cleansing, the % of cleansed fluid regions was 5.5%, 16.5% and 93.1% (p<0.0001 Chi square) for these groups respectively. Conclusion: A less-stressful bowel preparation with low residue diet and MD-Gastroview oral contrast is feasible for VC screening with follow-up biopsy on the positive findings by OC.
机译：目的：通过虚拟结肠镜检查（VC）探讨息肉筛选的息肉筛选，通过光学结肠镜检查（OC）对阳性发现进行后续活检。材料和方法：五十八岁年龄较大的年龄较大于40岁 - 接受柠檬酸镁的低残基饮食和泻药，双歉一性片和栓剂 - 分为三组。在第I群中，在VC程序前的一天，16名志愿者分别用三餐用三餐服用了三种40cc口服剂量的MD-Gastroview。在II族中，18名志愿者在睡前摄取硫酸钡悬浮液（2％w / v，250cc /剂量），并在vc的第二天早晨。在第三组，24名志愿者在睡前和第二天早上收到了60毫升的MD-Gastroview。结肠通胀后，通过标准单片检测器 - 带VC协议，即5毫米准直，重建，1.5-2.0：1.0间距，120 kVp和100-150，通过标准的单片探测器 - 带Vc协议获得计算机断层扫描（CT）腹部图像。嘛。测量标记残余流体的CT密度。施加图像分割算法以将电子方式除去残余物流体。结果：II2组，221u，III组，221u，III组，平均液体密度为97u，为221次HU。这三组的密度意味着显着不同（P <0.001单向ANOVA）。电子清洁后，净化的流体区域的百分比分别为这些组的5.5％，16.5％和93.1％（P <0.0001 Chi Square）。结论：具有低残留饮食和MD-GASTROVIEW口腔对比的较轻的肠道制剂对于VC筛选是可行的，在OC的阳性发现上具有随访活组织检查。

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