首页> 外文会议>Current Research on Laser Use in Oncology >Changes in the aqueous phase of cell suspensions and protein solutions induced by a photoexitation of the molecular oxygen (to mechanisms of biological action of low level laser radiation )
【24h】

Changes in the aqueous phase of cell suspensions and protein solutions induced by a photoexitation of the molecular oxygen (to mechanisms of biological action of low level laser radiation )

机译:细胞悬浮液水相的变化和分子氧的光再发出诱导的蛋白质溶液(对低水平激光辐射的生物作用机理)

获取原文

摘要

Temperature-dependent transient processes initiated by a direct photogeneration of singlet oxygen in suspensions of human erythrocytes and solutions of serum albumin are studied. The processes appear as anomalous jumps in the temperature dependences of the deformability coefficient of erythrocytes and the refractive index of the extracellular medium and protein solution. In the temperature regions of anomalous jumps, cells and proteins transfer to a metastable state of a lower activity, but they can be isothermally photoreactivated. Simultaneously, a reversible rearrangement of the aqueous phase occurs near the cell and protein surfaces, accompanied by the formation of an extended corona (hydrogel). The transient processes are interpreted as phase transitions in the membrane of erythrocytes and conformation transitions in proteins. The interaction between erythrocytes and albumin via hydrogel is discovered (hydro-conformational interaction).
机译:研究了通过单次氧气的直接荧光在人红细胞悬浮液中引发的温度依赖性瞬态过程,以及血清白蛋白的溶液。该过程在红细胞可变形系数的温度依赖性和细胞外介质和蛋白质溶液的折射率的温度依赖中出现异常跳跃。在异常跳跃的温度区域中,细胞和蛋白质转移到较低的活性的亚稳态,但它们可以是等温的光敏。同时,通过形成延长的电晕(水凝胶),在细胞和蛋白质表面附近发生含水相的可逆重排。瞬时过程被解释为红细胞膜中的相变,蛋白质中的兼容转变。发现了红细胞和白蛋白通过水凝胶的相互作用(水性构象相互作用)。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号