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Mathematical modeling of clearing liquid penetration into the skin

机译：清除液体渗透到皮肤中的数学模型

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The mathematical model of clearing agent penetration at topical administration of the agent on skin surface has been developed. Two-dimensional plane case has been considered. Skin was presented as multilayer medium with different diffusion coefficients in each layer and boundary conditions between adjacent layers. Analytical solution of the boundary problem has been obtained and approximation for large time interval has been derived.

机译：已经开发出在皮肤表面上局部施用试剂渗透的清除剂渗透的数学模型。已经考虑了二维平面案例。皮肤作为多层介质作为多层介质，每个层中的不同扩散系数和相邻层之间的边界条件。已经获得了边界问题的分析解决方案，并导出了大的时间间隔的近似。

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来源
《Saratov Meeting》|2007年||共7页
会议地点
作者
Mikhail M. Stolnitz; Alexey N. Bashkatov; Elina A. Genina; Valery V. Tuchin;
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原文格式 PDF
正文语种
中图分类光、激光生物医学;
关键词
clearing agent; skin penetration; diffusion; mathematical model;

机译：清除剂;皮肤渗透;扩散;数学模型;

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2. In-silico model of skin penetration based on experimentally determined input parameters. Part II: Mathematical modelling of in-vitro diffusion experiments. Identification of critical input parameters. [J] . Naegel A, Hansen S, Neumann D, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2008,第2期

机译：基于实验确定的输入参数的皮肤渗透的计算机模型。第二部分：体外扩散实验的数学模型。识别关键输入参数。
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4. Mathematical modeling of clearing liquid penetration into the skin [C] . Mikhail M. Stolnitz, Alexey N. Bashkatov, Elina A. Genina, Saratov Meeting . 2007

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5. Polymeric nanospheres for skin penetration enhancement: In vitro and in vivo assessment in skin models [D] . Batheja, Priya B. 2010

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7. Modelling of gas-liquid reactors - implementation of the penetration model in dynamic modelling of gas-liquid processes with the presence of a liquid bulk [O] . Elk, van, EP, Borman, PC, Kuipers, JAM Hans, 2000

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Mathematical modeling of clearing liquid penetration into the skin

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