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Investigation of glucose-hemoglobin interaction by optical coherence tomography

机译：光学相干断层扫描的葡萄糖血红蛋白相互作用研究

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摘要

In this study, the refractive index of glucose-hemoglobin solutions at different glucose concentrations was measured. Measurements were performed using Abbe refractometer at 589 nm and OCT system at 1300 nm. The different amount of glucose was added to hemoglobin solution. Theoretical values of refractive index of the glucose-hemoglobin solutions were calculated in assumption that hemoglobin and glucose molecules do not interact. The difference between the measured and calculated values of refractive index can be connected with glucose binding to hemoglobin. It is shown that the refractive index measurements can be applied to the evaluation of glycated hemoglobin amount.
机译：在该研究中，测量不同葡萄糖浓度下的葡萄糖血红蛋白溶液的折射率。使用Abbe折射计在1300nm处使用Abbe折射计进行测量。将不同量的葡萄糖加入血红蛋白溶液中。假设血红蛋白和葡萄糖分子不相互作用，计算葡萄糖血红蛋白溶液折射率的理论值。折射率的测量值和计算值之间的差异可以与血红蛋白的葡萄糖结合连接。结果表明，折射率测量可以应用于糖化血红蛋白量的评估。

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