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首页> 外文会议>IEEE RAS EMBS International Conference on Biomedical Robotics and Biomechatronics >Diaphragmatic electromyography analysis during two different mechanical ventilation techniques in patients with neuromuscular diseases
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Diaphragmatic electromyography analysis during two different mechanical ventilation techniques in patients with neuromuscular diseases

机译：两种不同机械通风技术中的神经肌病患者两种不同机械通风技术的膈肌探测分析

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摘要

The aim of the present study is to analyse changes in the diaphragmatic electromyography integral, as a direct expression of the patients inspiratory effort and index of neural respiratory drive, and parameters associated with ventilatory function in patients with prolonged weaning under Pressure Support Ventilation (PSV) and Neurally Adjusted Ventilatoy Assist (NAVA). Five patients affected by neuromuscular diseases were recruited. Each patient underwent a sequence of decreasing inspiratory support levels under NAVA and PSV, randomly assigned, from a baseline to a final level. At baseline, the value of diaphragmatic electromyography integral was higher under NAVA compared to PSV and increased in both ventilation modes progressing to final level. Higher values of inspiratory time and neural inspiratory time were observed in PSV at final level compared to baseline level. Conversely, a significant decrease of neural inspiratory time from baseline level to final level was observed in NAVA. Tidal volume at final level was significantly lower than at baseline level in both ventilation modes. These preliminary results show that in prolonged weaning patients affected by neuromuscular disease NAVA ventilation is associated to a higher diaphragmatic electromyography activity compared to PSV with same level of ventilation and subjective comfort.
机译：本研究的目的是分析在膈肌电积分的变化，患者吸气努力和呼吸中枢驱动的索引，并在压力支持通气患者通气功能相关联的与延长断奶参数的直接表达（PSV）和Neurally调整Ventilatoy辅助（NAVA）。受神经肌肉疾病5例患者招募。每个病人接受降低NAVA和PSV下吸气支持级别的序列，随机分配，从基线到最终水平。在基线时，膈肌肌电积分值是NAVA在较高相比，PSV和两个通气模式发展到最后水平的提高。在PSV观察到在最后一级的吸气时间和神经吸气时间值越高，相对于基线水平。相反，在NAVA观察到神经吸气时间显著减少从基线水平到最终水平。在最后一级潮气量明显高于在两个通气模式基线水平显著降低。这些初步结果表明，受神经肌肉疾病NAVA通气延长断奶患者关联到比较PSV通风和主观舒适的同一水平较高的膈肌肌电活动。

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