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Immuno pathologic mechanisms in drug hypersensitivity

机译：免疫病理机制在吸毒超敏反应中

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ADVERSE DRUG REACTIONS 1 - Dose dependent, related with pharmacological effect of the drug 2 - Dose independent not related to the main pharmacological effect of the drug - Non-immune mediated - Immune mediated: Drug hypersensitivity reaction.IMMUNOLOGIC MECHANISMS IN HYPERSENSITIVITY DRUG REACTIONS 1 -The Host System HLA and Drug reactions. Interaction between innate and adaptive immune system 2 - The Drugs Drugs and metabolites 3 - Host Drugs - Interactions Cellular and molecular mechanisms of reactions to drugs 4 - Classification of drug reactions.THE HOST 1 - HLA AND DRUG HYPERSENSITIVITY 2 - INNATE IMMUNE RESPONSES AND DRUG HYPERSENSITIVITY HLA THE HOST AND DRUG HYPERSENSITIVITY HLA class I (HLA-A, HLA-B, HLA-C).

机译：不良药物反应1 - 剂量依赖，与药物2剂的药理作用有关与药物的主要药理作用无关 - 非免疫介导 - 免疫介导的主要药理作用：药物超敏反应。过敏药物反应的免疫机制1 - 宿主系统HLA和药物反应。先天和自适应免疫系统2的相互作用2 - 药物药物和代谢物3 - 宿主药物 - 相互作用和药物反应的分子机制4 - 药物反应的分类。宿主1 - HLA和药物超敏反应2 - 先天性免疫应答和药物超敏感性HLA宿主和药物超敏HLA I类（HLA-A，HLA-B，HLA-C）。

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《World Asthma COPD Forum》|2011年||共6页
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Palma-Carlos A.G.; E Faaai; Hdfacai Palma-Carlos M.L.;
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4. Immuno pathologic mechanisms in drug hypersensitivity [C] . Palma-Carlos A.G., E Faaai, Hdfacai Palma-Carlos M.L. World Asthma COPD Forum . 2011

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6. Editorial: Drug Hypersensitivity: From Mechanisms to Improved Diagnosis and Standards of Care [O] . T. D. Fernandez, M. J. Torres, A. Romano 2021

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7. Delayed hypersensitive reaction in patient with MRA and effect of immuno-modulating drugs for mouse and RA patient [O] . Koji Sagawa 1981

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8. Biologic Reactions of Cellular Antibodies with Special Reference to Their Immuno-Pathological and Immuno-Chemical Properties [R] . Hayashi, H. 1969

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Immuno pathologic mechanisms in drug hypersensitivity

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