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Different protein profile in amniotic fluid with nervous system malformations by SELDI-TOF-MS technology

机译:Seldi-Tof-MS技术具有神经系统畸形的羊水中的不同蛋白质谱

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To detect the distinct proteins in amniotic fluid between nervous system malformations fetuses and normal fetuses. Surface-enhanced laser desorption-ionization/time-of-flight mass spectrometry was used to characterize amniotic fluid peptides in amniotic fluid between nervous system malformations fetuses and normal fetuses. Protein chips were used to characterize amniotic fluid peptides in amniotic fluid. Protein chips were examined in protein reader, the protein profiling was collected by proteinchip software 3.1 and analyzed by Biomarker Wizard software. Nine distinct proteins were identified in amniotic fluid between nervous system malformations fetuses and normal fetuses. The results suggest that there are distinct proteins in protein profiling of amniotic fluid between nervous system malformations fetuses and normal fetuses.
机译:在神经系统畸形胎儿和正常胎儿之间检测羊水中的不同蛋白质。表面增强的激光解吸离电离/飞行时间质谱法用于在神经系统畸形胎儿和正常胎儿之间表征羊水中的羊水肽。使用蛋白质芯片在羊水中表征羊膜肽。在蛋白质读取器中检查蛋白质芯片,通过蛋白质芯片软件3.1收集蛋白质分析,并通过生物标志物向导软件进行分析。在神经系统畸形胎儿和正常胎儿之间在羊水中鉴定了九种不同的蛋白质。结果表明,神经系统畸形胎儿和正常胎儿之间的羊水蛋白质分析中存在明显的蛋白质。

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