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首页> 外文会议>International Conference on Medical Physiology >Postnatal creatinemia in extremely low birth weight (ELBW) neonates reflects perinatal renal maturational physiology
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Postnatal creatinemia in extremely low birth weight (ELBW) neonates reflects perinatal renal maturational physiology

机译：产后植物血症极低出生体重（elbw）新生儿反映了围产期肾养殖生理学

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摘要

To assess perinatal renal physiology is extreme low birth weight (ELBW, <1000g) neonates, prenatal covariates [betamethasone, preterm rupture of membranes (PPROM), pre-eclampsia, maternal Scr], at delivery [gestational age (GA), birth weight (BW), small for GA (SGA), Apgar, intubation] and during neonatal stay [ventilation, oxygen, parenteral nutrition, ibuprofen, steroids, intraventricular haemorrhage, retinopathy of prematurity (ROP)] were linked with Scr (mg/dl) (day 1-9, 14, 21, 28, 42, peak Scr). Based on observations in 151 ELBW neonates [GA 27(23-33) weeks, BW 810(370-1000) g, SGA 34%], an initial increase in Scr was observed resulting in a peak Scr on day 3 or 4 (1.13,0.53-2.51) with subsequent decrease. Multiple and logistic regression confirmed that GA and ventilation or Apgar were independent risks factors for renal impairment. ELBW neonates display similar Scr trends compared to heavier neonates, but peak Scr is higher, its subsequent decrease slower. Renal impairment in ELBW neonates reflects immaturity and morbidity.
机译：为了评估围产期肾生理学是极端的低出生体重（ELBW，<1000g）新生儿，产前协变量[β塞酮，膜（PPROM），前罕见，母体瘢痕疙瘩，母体SCR]，在递送[妊娠期（GA），出生体重（BW），小于GA（SGA），APGAR，插管]和新生儿停留期间[通风，氧气，肠胃外营养，布洛芬，类固醇，脑室内出血，与SCR（MG / DL）有关，可治疗（ROP）的视网膜病变（第1-9,14,14,21,28,22，峰SCR）。基于151 ELBW新生儿[GA 27（23-33）周，BW 810（370-1000）G，SGA 34％]，观察到SCR的初始增加，导致第3天或4天（1.13 ，0.53-2.51）随后减少。多元和逻辑回归证实，GA和通风或APGAR是肾脏损伤的独立风险因素。 Elbw Neonates与较重的新生儿相比显示了类似的SCR趋势，但峰SCR更高，其随后的减少较慢。 Elbw Neonates肾脏损伤反映了不成熟和发病率。

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