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Lessons Learned from Prevention Programs:Different Endpoints Should Be Used in Secondary and Tertiary Prevention

机译:从预防计划中吸取的经验教训:不同的终点应该用于二级和三级预防

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It is mandatory to compare cost and consequences of healthcare services if public support is requested. This request will apply to all healthcare services including prevention. As the demand for health care will always exceed the available resources, methods that make it possible to select the "best" programs for implementation have to be developed. The selection of the "best" programs is not easy because there exist so far no generally accepted quality criteria that can be used to identify the "best" prevention programs.Based on a model on structural and functional properties of a disease, it is concluded that the traditional outcomes of treatment and prevention may be useful for the evaluation of tertiary prevention programs, but not of secondary prevention programs. Neither the traditional endpoints of treatment studies nor traditional surrogate parameters are useful for the evaluation of secondary prevention programs.Using the assumptions of the model and a list of available data in secondary prevention programs we recommend to assess five indicators for description of the value of a secondary prevention program: quality of life, surrogates for life expectancy, the perspective of the assessor, the conditions of assessment, and finally the payment. As each of these five items offers two possible values prevention programs may be classified into 32 different groups.
机译:它是强制性的,如果被请求公众支持来比较成本和医疗服务的后果。这要求将适用于所有的医疗保健服务,包括预防。至于医疗保健的需求将始终超过可用的资源,也使人们有可能选择执行“最佳”方案的方法就必须开发。 “最佳”方案的选择是不容易的,因为存在可用于识别programs.Based关于疾病的结构和功能特性的模型“最佳”预防迄今尚无公认的质量标准,可以得出结论:是治疗和预防的传统结局可能是三级预防方案的评价是有用的,但不是二级预防方案。无论治疗研究,也没有传统的代理参数的传统的端点是二级预防programs.Using模型的假设和二级预防方案可用数据的列表的评估有用的建议,以评估的价值的描述五项指标二级预防方案:生活质量,替代物寿命,评估的角度,评估的条件,最后付款。由于上述五个项目提供两个可能值的预防方案可分为32个不同的组。

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