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Molecular Aspects of Intraductal Papillary Mucinous Neoplasms

机译:Intructal乳头状粘液瘤的分子方面

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Intraductal papillary mucinous neoplasms (IPMNs) are characterized by the cystic dilation of pancreatic ducts lined with mucin-producing atypical epithelium showing papillary growth. The recognition of IPMNs of the pancreas is increasing. However, there are no reliable methods to evaluate the malignant potential of an IPMN, which leads to difficulty in clinical management. Novel biomarkers are needed to preoperatively evaluate the malignant potential of an IPMN, and for this purpose, many molecular analyses have been performed.
机译:内部乳头状粘液瘤(IPMNS)的特征在于胰管的囊性扩张,胰酸的产生粘蛋白产生的非典型上皮性显示出乳头状生长。对胰腺的IPMNS的识别正在增加。然而,没有可靠的方法来评估IPMN的恶性潜力,这导致临床管理难以困难。需要新的生物标志物来术前评价IPMN的恶性潜力,为此目的,已经进行了许多分子分析。

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