• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文会议>International Conference on Chemical Engineering and Advanced Materials >Depressions of Urinary Crystallites: A Direct Proof of Citric Acid Dissolving Calcium Oxalate Stones in Vivo
【24h】

Depressions of Urinary Crystallites: A Direct Proof of Citric Acid Dissolving Calcium Oxalate Stones in Vivo

机译：尿液凹陷：体内柠檬酸溶解钙碳酸钙的直接证明

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Scanning electron microscopy (SEM), X-ray power diffraction (XRD) and Zeta potential (ξ) analyzer were used to investigate the changes of morphology, species, crystal quantity, ξ, and aggregation state of urinary crystallites of calcium oxalate (CaOxa) stone formers before and after taking drug potassium citrate (K_3cit). Before taking K_3cit the edges and corners of urinary crystallite were sharp and aggregated significantly, the main components were uric acid, calcium oxalate monohydrate (COM) and phosphate, etc. While after taking K_3cit for one week, some of urinary crystallites became blunt, the aggregated crystallites and the species of crystallites were obviously reduced, the amount of uric acid was reduced, but the percentage of calcium oxalate dihydrate (COD) and the absolute value of ξ increased. Especially crystal depressions emerged at the surface of some crystallites, which was the direct proof of K_3cit dissolving CaOxa stones in vivo. From the point of coordination between K_3cit and Ca~(2+), the increase of pH and citric acid concentration excreted in urine after taking K_3cit, the mechanism of how K_3cit inhibit the formation of COM stones was discussed.
机译：扫描电子显微镜（SEM），X射线功率衍射（XRD）和Zeta电位（ξ）分析仪用于探讨草酸钙（CAOXA）尿液结晶的形态，物种，晶体量，χ和聚集状态的变化服用柠檬酸钾（K_3cit）之前和之后的石头饲养剂。在服用K_3CIT之前，尿液结晶石的边缘显着剧烈，主要成分是尿酸，草酸钙一水合物（COM）和磷酸盐等。同时服用K_3cit一周后，一些尿液结晶变得钝聚集的微晶和微晶种明显降低，降低了尿酸的量，但草酸钙二水合物（COD）的百分比和Ⅳ的绝对值增加。特别是在一些微晶表面的水晶凹陷中出现，这是溶解曹氏菌在体内K_3cit的直接证明。从K_3Cit和Ca〜（2+）之间的协调点，讨论了K_3cit后尿液中pH和柠檬酸浓度的增加，讨论了K_3CIT如何抑制COM石头的形成的机制。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号