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Carbon Nanotubes: Biorisks and Biodefence

机译:碳纳米管:生物风险和生物灌注

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摘要

From the time of the discovery of carbon nanotubes (CNT) the question of their toxicity remains of key importance. The practical use of these unique nano-materials in biotechnology, molecular biology and medicine can be complicated because of possible adverse effect of CNT on subcellular and cellular structures, tissues and whole organs. Similarly to any other nanoparticles, CNT toxicity is defined by their form, size, purity, charge, dose, entry route into the body, concentration in the target organ, duration of contact and other factors. The research on toxicity and biocompatibility of CNT of different origin, structure and purity began in 2001. It has been conducted with various biological components, performing experiments both in vitro and in vivo. Here some aspects of cytotoxicity and potential for medical use of CNT are discussed.
机译:从发现碳纳米管(CNT)的发现,他们的毒性问题是重要的重要性。由于CNT对亚细胞和细胞结构,组织和整个器官的可能不良影响,这些独特的纳米材料在生物技术,分子生物学和药物中的实际应用可能是复杂的。与任何其他纳米颗粒类似,CNT毒性由其形式,尺寸,纯度,电荷,剂量,进入途径定义为身体,靶器官中的浓度,接触持续时间和其他因素。 2001年开始研究不同起源,结构和纯度CNT的毒性和生物相容性。它已经用各种生物成分进行,在体外和体内进行实验。这里讨论了细胞毒性的一些方面和CNT的医学用潜力。

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