DEOXYSCHIZANDRIN AND y-SCHIZANDRIN RESTORE THE CYTOTOXIC ACTION OF DOXORUBICIN IN MULTI-DRUG RESISTANT LUNG CANCER CELLS COR-L23/R

机译：Deoxyschizandrin和Y-Schizandrin恢复多种毒性肺癌细胞Cor-L23 / R的多柔比星的细胞毒性作用

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Dibenzo[a,c]cyclooctadiene lignans are natural products occurring in Schisandra chinensis (Schisandraceae), a well-known medicinal plant in traditional Chinese medicine. The fruits and seeds have been used for centuries as a tonic and antitussive and many studies have indicated that the active ingredients are lignans possessing an unusual structure derived from dibenzo[a,c]cyclooctadiene (Figure 1). These lignans have been shown to exhibit a broad range of biological effects, including hepatoprotective and antiviral properties. Recently, dibenzocyclooctadiene lignans have been discussed as compounds that are able to overcome multidrug resistance.

机译：二苯苯基[A，C] Cycloctadiene Lignans是Schisandra Chinensis（Schisandraceae）发生的天然产物，该植物在中药着名的药用植物。果实和种子已被几个世纪以来作为滋补和镇咳，并且许多研究表明，活性成分是具有衍生自二苯苯甲基[A，C]环辛二烯的异常结构的木质体（图1）。这些木质素已被证明表现出广泛的生物学作用，包括肝脏保护和抗病毒性质。最近，二苯苄溶细胞辛二烯木质素已被讨论为能够克服多药抗性的化合物。

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《Proceedings of Functional Molecules from Natural Sources》|2011年||共6页
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Jin Slanina; Lenka Adamkova; Ludmila Koubikova;
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中图分类化学;
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DEOXYSCHIZANDRIN AND y-SCHIZANDRIN RESTORE THE CYTOTOXIC ACTION OF DOXORUBICIN IN MULTI-DRUG RESISTANT LUNG CANCER CELLS COR-L23/R

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