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Open or minimally invasive resection for oesophageal cancer?

机译:对食管癌开放或微创切除术?

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Oesophagectomy is one of the most challenging surgical operations. Potential for morbidity and mortality is high. Minimally invasive techniques have been introduced in an attempt to reduce postoperative complications and recovery times. Debate continues over whether these techniques decrease morbidity and whether the quality of the oncological resection is compromised. Globally, minimally invasive oesophagectomy (MIO) has been shown to be feasible and safe, with outcomes similar to open oesophagectomy. There are no controlled trials comparing the outcomes of MIO with open techniques, just a few comparative studies and many single institution series from which assessments of the current role of MIO have been made. The reported improvements of MIO include reduced blood loss, shortened time in high dependency care and decreased length of hospital stay. In comparative studies there is no clear reduction in respiratory complications, although larger series suggest that MIO may have a benefit. Although MIO approaches report less lymph node retrieval compared with open extended lymphadenectomy, MIO cancer outcomes are comparable. MIO will be a major component of the future oesophageal surgeons' armamentarium, but should continue to be carefully assessed.Randomized trials comparing MIO versus open resection in oesophageal cancer are urgently needed: two phase III trials are recruiting, the TIME and the MIRO trials.
机译:Oesophagecectomy是最具挑战性的手术作业之一。发病率和死亡率的潜力很高。已经引入了微创技术,以试图减少术后并发症和恢复时间。辩论继续过度这些技术是否会降低发病率,以及肿瘤切除术的质量是否受到损害。在全球范围内,微创OESOPHAGECTOMY(MIO)已被证明是可行和安全的,结果类似于露天切除术。没有受控试验比较MIO与开放式技术的结果,只是一些比较研究和许多单一机构系列,从中已经进行了目前的MIO作用评估。报告的MIO改善包括降低血液损失,缩短时间高依赖护理和减少的住院时间。在比较研究中,呼吸并发症中没有明确降低,尽管较大的系列表明MIO可能有益。尽管与开放的延长淋巴结切除术相比,MIO方法报告较少的淋巴结检索,但MIO癌症结果是可比的。 MIO将成为未来食管外科医生的主要组成部分的植物园,但应继续进行仔细评估。迫切需要进行比较MIO与OeSophageal癌症的开放切除比较的方法:两期III阶段试验正在招聘,时间和MIRO试验。

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