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Form Follows Function Model-Driven Engineering for Clinical Trials

机译:表格遵循功能模型驱动的临床试验工程

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We argue that, for certain constrained domains, elaborate model transformation technologies - implemented from scratch in general-purpose programming languages - are unnecessary for model-driven engineering; instead, lightweight configuration of commercial off-the-shelf productivity tools suffices. In particular, in the CancerGrid project, we have been developing model-driven techniques for the generation of software tools to support clinical trials. A domain metamodel captures the community's best practice in trial design. A scientist authors a trial protocol, modelling their trial by instantiating the metamodel; customized software artifacts to support trial execution are generated automatically from the scientist's model. The metamodel is expressed as an XML Schema, in such a way that it can be instantiated by completing a form to generate a conformant XML document. The same process works at a second level for trial execution: among the artifacts generated from the protocol are models of the data to be collected, and the clinician conducting the trial instantiates such models in reporting observations - again by completing a form to create a conformant XML document, representing the data gathered during that observation. Simple standard form management tools are all that is needed. Our approach is applicable to a wide variety of information-modelling domains: not just clinical trials, but also electronic public sector computing, customer relationship management, document workflow, and so on.
机译:我们认为,对于某些受限制的域来说,精心制定的模型转型技术 - 从划痕中实现的通用编程语言 - 模型驱动工程是不必要的;相反,轻量级配置商业现成的生产力工具就足够了。特别是在CancerGrid项目中,我们一直开发用于生成软件工具的模型驱动技术,以支持临床试验。域Metamodel捕获了社区在试验设计中的最佳实践。一位科学家作者通过实例化元模型来模拟他们的试验;自定义软件以支持试用执行的工件自动从科学家的模型生成。元模型表示为XML模式,以这样的方式,可以通过完成形式来生成符合XML文档来实例化。同一过程在第二级工作进行试用:在协议生成的工件中是要收集的数据的模型,并且临床医生进行试验的临床医生在报告观察中实例化这些模型 - 再次完成一种形式以创建一个符合性XML文档,表示在该观察期间收集的数据。简单的标准表单管理工具是所需的。我们的方法适用于各种信息建模领域:不仅仅是临床试验,还可以是电子公共部门计算,客户关系管理,文件工作流等。

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