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Prevalence and Risk Factors for the Development of Glaucoma After Penetrating Keratoplasty in a Tertiary Hospital

机译:高等院医院渗透角膜术后青光眼发展的患病率和风险因素

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Objective: To determine the prevalence and risk factors for the development of glaucoma afterpenetrating keratoplasty (PKP) done at the Philippine General HospitalMethods: This is a retrospective chart review of patients who underwent PKP at the Philippine GeneralHospital (PGH) between January 1, 2005 and March 31, 2012. Indications for PKP were recorded. Outcomemeasures were classified into either of four categories: No glaucoma, temporary glaucoma, medically controlledglaucoma, and surgical glaucoma. Ordinal logistic regression was performed using Stata Data Analysis andStatistics Software.Results: A total of 222 cases were included in the study. The prevalence of post-PKP glaucoma was41.44% (92 eyes). Medical glaucoma escalation developed in 21.2% (47 eyes) of the cases while 20.3% (45eyes) developed surgical glaucoma escalation. The prevalence of ocular hypotony was 8.1% (18 eyes). Fungalkeratitis (26.7%) and bacterial keratitis (22.0%) were the top 2 indications for performing PKP accounting for49.6% (110 cases). These were followed by post-surgical bullous keratopathy (19.6%), viral keratitis (8.4%),and corneal scar (6.4%). Age was a significant risk factor for the development of glaucoma (P = 0.005, RR =1.02). Vitrectomy (P = 0.005), IOL explantation (P = 0.022), and trans-scleral suture intraocular lens (TSS-IOL)implantation (P = 0.022), when performed with PKP, were significant risk factors for the development ofglaucoma. Large recipient trephination size and ruptured fungal keratitis were risk factors for the development ofocular hypotony.Conclusion: The prevalence of post-PKP glaucoma in this group of patients was 41.4%. Risk factorsfor the development of post-PKP glaucoma include increasing age and performing vitrectomy, IOL explantation,or TSS-IOL implantation together with the PKP. Large recipient trephination size and ruptured fungal ulcerswere significant risk factors for the development of ocular hypotony.
机译:目的:确定在菲律宾总医院治疗术后青光眼发展的患病率和风险因素(PKP):这是2005年1月1日至2005年1月1日期间菲律宾通用(PGH)的PKP患者的回顾性图表综述。 2012年3月31日。记录了PKP的迹象。 OutComemeSess分类为四类中的任一类:无青光眼,临时青光眼,医学控制纤维瘤和外科葡萄糖。使用STATA数据分析Antstatistics软件进行序数逻辑回归。结果:研究中共有222例。 PKP后青光眼的患病率为41.44%(92只眼)。医疗青光眼升级在21.2%(47只眼)的情况下,而20.3%(45eyes)发育了外科青光眼升级。眼镜慢亢进的患病率为8.1%(18只眼)。 Fungalkeratitis(26.7%)和细菌角膜炎(22.0%)是表演PKP占49.6%的前2名适应症(110例)。这些后面是手术后大疱性角质病(19.6%),病毒角膜炎(8.4%)和角膜疤痕(6.4%)。年龄是青光眼发展的重要风险因素(P = 0.005,RR = 1.02)。玻璃体切除术(P = 0.005),IOL脱盐(P = 0.022)和反式巩膜缝合型眼透镜(TSS-IOL)植入(P = 0.022),当用PKP进行时,为Gllaucoma的发育是显着的风险因素。大量的受体曲线大小和破裂的真菌角膜炎是一种柔道的低步骤的风险因素。结论:这群患者PKP后青光眼的患病率为41.4%。 PKP后青光眼发展的风险因素包括增加年龄并进行玻璃体切除术,IOL脱盐或TSS-IOL植入。大量的受体曲线大小和破裂的真菌Ulcerswerswers对眼部低位的发展的重大风险因素。

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