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Interaction of fructose with other medium components to affect bioproduction of docosahexaenoic acid (DHA) by Aurantiochytrium sp. SW1

机译:果糖与其他培养基组分的相互作用影响二氧化碳氧化乙烯酸(DHA)的生物处理SP。 SW1.

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Thraustochytrids are a group of marine fungus-like microheterotrophs of which some can accumulate considerable amounts of the high valued omega-3 oil, docosahexaenoic acid (DHA). In this study, a local thraustochytrid isolate, Aurantiochytrium sp. SW1, was cultivated in a medium containing fructose as the major carbon source. The effects of this carbon source in interaction with yeast extract, monosodium glutamate (MSG) and sea salt were studied using a software-based two level full factorial design. Results showed that fructose as a single factor, has significant positive effect on the volumetric DHA content of SW1. Similarly, its interaction with yeast extract has profound positive effect. However, interactions of fructose with MSG and sea salt were significant negative effects. These results indicate that manipulation of the concentration of fructose in the culture medium may serve as a simple and useful strategy to help achieve preferred amount of DHA.
机译:Thraustochytrids是一组海洋真菌样片,其中有些人可以积累大量大量的高价值ω-3油,二十二碳酸(DHA)。在本研究中,局部Thraustochytrid孤立,Aurantiochytrium sp。 SW1,在含有主要碳源的培养基中培养。使用基于软件的两个完整的因子设计研究了这种碳源与酵母提取物的相互作用的影响,研究了基于软件的两个完整的因子设计。结果表明,果糖作为单一因素,对SW1的体积DHA含量具有显着的阳性作用。类似地,其与酵母提取物的相互作用具有深刻的阳性作用。然而,果糖与MSG和海盐的相互作用是显着的负面影响。这些结果表明,培养基中果糖浓度的操纵可以用作有助于获得优选的DHA的优选量的简单和有用的策略。

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