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Historical exposure to arsenic in drinking water and risk of late fetal and infant mortality-Chile 1950-2005

机译:1950 - 2005年饮用水中饮用水中砷和婴儿死亡风险的历史暴露,智利

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A previous study comparing two Chilean cities demonstrated significant increase in fetal mortality in relation to increase in arsenic (As) exposure. Our aim was to confirm this association increasing size and variation of the comparison group, extending the time interval and measuring additional potential confounders. We used time series analysis of infant mortality indicators. We confirmed the clear excess of risk of late fetal death following the increase of the As concentration in drinking water, and the rapid return to the baseline mortality rate in response to the removal of arsenic after 1973. The effect was lower for neonatal and post-neonatal mortality. This study confirms that fetus is more sensitive to As and that regulations should consider additional protection for pregnant women and small children.
机译:比较两位智利城市的先前研究表明,胎儿死亡率的显着增加是砷(AS)暴露的增加。我们的目的是确认这种关联的规模和变化的比较组,扩展时间间隔和衡量额外的潜在混杂。我们使用时间序列分析婴儿死亡率指标。在饮用水中的浓度增加后,我们确认了晚期胎儿死亡的风险过多,以及1973年以后去除砷的快速返回基线死亡率。新生儿和后的效果较低新生儿死亡率。本研究证实,胎儿对胎儿更敏感,而该法规应考虑对孕妇和小孩子的额外保护。

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