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High-Throughput Genome-Wide Genotyping to Revive the Use of Natural Diversity in Forage and Turf Breeding

机译:高通量基因组基因分型,以恢复饲料和草皮育种中的自然多样性

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European genebanks maintain collections of natural accessions of forage and turf species that represent a wide sampling of the adaptive diversity existing in these species. The increasing availability of technologies for the screening of genome-wide polymorphisms offers challenging opportunities to search for genomic diversity involved in the adaptive response of natural populations. New high-throughput genotyping technologies can be combined with information from environmental databases covering large spatial scales at fine resolution to search for associations between genomic polymorphisms and environmental variation at sites of origin of the natural diversity. Furthermore, methods to detect signature of selection using dense genome-wide genotyping data have been developed from population genetics theory. This methodological framework is well suited for studies at the macro-environmental level, which is the relevant level to investigate adaption to climatic constraints. We suggest it can be applied to genebank accessions collected throughout the natural distribution area of forage and turf species, in order to provide a new kind of information to guide the use of natural diversity in breeding programs.
机译:欧洲Genebanks维持饲料和草皮种类的自然摘要集合,这些物种代表了这些物种中存在的自适应多样性的广泛取样。筛查基因组多态性的筛选技术的增加提供了挑战的机会,以寻找参与自然群体适应性响应的基因组多样性。新的高吞吐学基因分型技术可以与环境数据库的信息相结合,这些数据库以精细分辨率覆盖大型空间尺度,以搜索自然多样性的原产地基因组多态性和环境变异之间的关联。此外,已经从群体遗传学理论中开发了使用致密基因组基因分型数据进行选择的方法。这种方法框架非常适合于宏观环境水平的研究,这是调查对气候限制适应的相关水平。我们建议它可以应用于整个牧草和草皮物种的自然分布区域收集的Genebank登录,以便提供新的信息,以指导在育种计划中使用自然多样性。

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