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Supercritical CO_2 extraction of γ-linolenic acid from Spirulina platensis

机译:Spirulina Platensis的超临界CO_2提取γ-亚麻酸

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Arthrospira (Spirulina) platensis contains large quantities of γ-linolenic acid (GLA). GLA is an essential omega-6 unsaturated fatty acid made in the human body from linoleic acid. It can be metabolized to various important eicosanoids such as prostaglandins, thromboxanes, leukotrienes, prostacyclins, and lipoxins. The aim of this study was to investigate the optimal extraction parameters of GLA from A. platensis using supercritical CO_2 technology. Results showed that operating temperatures and pressures were important factors in the extraction of GLA. A maximum GLA yield of 161.98 μg/g could be obtained at a pressure of 30 MPa, a temperature of 60°C, and a CO_2 flow rate of 6 mL/min. Conversely, only a yield of 104.16 μg/g could be obtained at a pressure of 10 MPa, a temperature of 40°C, and a CO_2 flow rate of 6 mL/min. The correlation between pressure and yield could be explained by an increase in collision rates between CO_2 molecules and carrier affinity under a high pressure. Therefore, an operating temperature between 50 and 60°C and a pressure of 30 MPa should be used to maximize the yield of GLA from A. platensis using supercritical CO_2 technology.
机译:arthrospira(螺旋藻)铂含有大量的γ-亚麻酸(Gla)。 GLA是亚油酸中的人体中的必需ω-6不饱和脂肪酸。它可以代谢到各种重要的七分异糖醇类,如前列腺素,血栓素,白三烯,前列腺和脂毒素。本研究的目的是使用超临界CO_2技术研究来自A.Platensis的GLA的最佳提取参数。结果表明,工作温度和压力是GLA提取的重要因素。在30MPa的压力下,温度为60℃的压力和6ml / min的CO_2流速,可以获得161.98μg/ g的最大GLA产率。相反,在10MPa的压力下,仅获得104.16μg/ g的产率,40℃的温度,以及6ml / min的CO_2流速。压力和产率之间的相关性可以通过在高压下的CO_2分子和载体亲和力之间的碰撞速率的增加来解释。因此,应使用50至60℃的工作温度和30MPa的压力来利用超临界CO_2技术来最大化来自A铂的GLA的产率。

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