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首页> 外文会议>Conference on advanced microscopy techniques IV >Identification of Malaria Infected Red Blood Samples by Digital Holographic Quantitative Phase Microscope
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Identification of Malaria Infected Red Blood Samples by Digital Holographic Quantitative Phase Microscope

机译：数字全息定量相显微镜鉴定疟疾感染红血样品

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Development of devices for automatic identification of diseases is desired especially in developing countries. In the case of malaria, even today the gold standard is the inspection of chemically treated blood smears through a microscope. This requires a trained technician/microscopist to identify the cells in the field of view, with which the labeling chemicals gets attached. Bright field microscopes provide only low contrast 2D images of red blood cells and cell thickness distribution cannot be obtained. Quantitative phase contrast microscopes can provide both intensity and phase profiles of the cells under study. The phase information can be used to determine thickness profile of the cell. Since cell morphology is available, many parameters pertaining to the 3D shape of the cell can be computed. These parameters in turn could be used to decide about the state of health of the cell leading to disease diagnosis. Here the investigations done on digital holographic microscope, which provides quantitative phase images, for comparison of parameters obtained from the 3D shape profile of objects leading to identification of diseased samples is described.
机译：尤其是在发展中国家所希望自动鉴定疾病的设备的开发。在疟疾的情况下，即使在今天的情况下，黄金标准也是通过显微镜检查化学处理的血液涂片。这需要训练有素的技术人员/显微镜，以识别视野中的细胞，其中标记化学品被连接。亮场显微镜仅提供红细胞的低对比度2D图像，不能获得细胞厚度分布。定量相对比显微镜可以提供所研究的细胞的强度和相形谱。相位信息可用于确定细胞的厚度分布。由于细胞形态可用，因此可以计算与单元的3D形状有关的许多参数。这些参数又可以用于决定导致疾病诊断的细胞的健康状况。这里描述了在数字全息显微镜上进行的调查，其提供定量相位图像，用于比较从导致鉴定患病样品的物体的3D形状分布所获得的参数。

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