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INFLAMMATORY BOWEL DISEASE (IBD) IN THE CANINE AND FELINE PATIENT

机译:犬和​​猫科动物患者的炎症性肠病(IBD)

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Inflammatory bowel disease (IBD) is the result of the accumulation of inflammatory cells within the lining of the stomach, small intestines and/or large intestines. IBD is distinguished by persistent, recurrent gastrointestinal (GI) signs and histological evidence of intestinal inflammation. Although the most common clinical signs are chronic vomiting and diarrhea, presenting complaints can include changes in appetite (hyporexia, anorexia or even polyphagia), weight loss, lethargy, abdominal distension, polyuria and polydipsia (PU/PD).The two most common forms of IBD are lymphocytic-plasmacytic enteritis (LPE) and eosinophilic enteritis (EE). LPE is characterized by infiltration of lymphocytes and/or plasma cells into the intestines. EE is characterized by eosinophilic infiltration ofany region of the intestinal mucosa. The exact etiology of IBD remains largely unknown. Environmental and genetic factors as well as abnormal immunologic responses are thought to play a large role however, at this time, IBD is thought to be idiopathic.
机译:炎症性肠病(IBD)是胃,小肠和/或大肠内衬里内炎症细胞积累的结果。 IBD以持续的,经常性的胃肠道(GI)症状和肠炎症的组织学证据而区分。虽然最常见的临床症状是慢性呕吐和腹泻,但呈现抱怨可包括食欲的变化(低温,厌食症,甚至多斑),减肥,嗜睡,腹胀,聚需要尿症和较副潜伏(PU / PD)。两个最常见的形式IBD是淋巴细胞 - 浆肠炎(LPE)和嗜酸性肠炎(EE)。 LPE的特征是浸润淋巴细胞和/或血浆细胞进入肠道。 EE的特征在于肠粘膜的嗜酸性渗透。 IBD的确切病因仍然很大程度上是未知的。然而,据认为,环境和遗传因素以及异常的免疫反应被认为是巨大的作用,因此IBD被认为是特发性的。

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