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Effect of the inflammatory conditions and albumin presence on the corrosion behavior of grade 5 Titanium alloy in saliva biological solution

机译:炎症条件和白蛋白存在对唾液生物溶液5级钛合金腐蚀行为的影响

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The field of biomaterials imposes a multidisciplinary approach that requires the involvement of sciences such as biology, medicine, chemistry and materials engineering so that the material implanted in a living organism does not cause any adverse reaction. This research area of biomaterials is considered as fascinating and challenging. It's fascinating because of its potential applications and the need to improve the quality of life. It is challenging due to the various complexities it faces when biomaterials encounter biological environments for the longevity of life by maintaining or restoring tissue or organ functions. Metallic biomaterials are used as pivots for anchoring dental implants and as parts of orthodontic devices such as crowns and bridges of prostheses. Ti-6A1-4V is well known as a corrosion resistant alloy for dentistry applications due to this film of titanium oxide formed on its surface. However, the inflammatory conditions ad protein presence could affect the corrosion resistance of this alloy. Our research work aims to investigate the effect of albumin and inflammatory conditions to corrosion resistance of Ti-6A1-4V in saliva Fusayama Meyer biological solution. In order to simulate the peri-implant inflammatory conditions in vitro studies were conducted with addition of hydrogen peroxide (reactive oxygen species, found during inflammation) and albumin the most typical protein of biological fluids. Electrochemical methods were applied for corrosion investigations. The results provide evidence that titanium's alloy corrosion resistance is affected by inflammatory conditions and albumin presence in saliva biological solution.
机译:生物材料领域征收多学科方法,需要涉及生物学,医学,化学和材料工程等科学,使得植入生物体中的材料不会引起任何不良反应。这种生物材料的研究领域被认为是令人着迷和挑战性的。由于其潜在的应用以及提高生活质量的需要,因此令人着迷。当通过维持或恢复组织或器官功能,生物材料遇到生物环境时,它面临的各种复杂性是具有挑战性的。金属生物材料用作锚固牙科植入物的枢轴,以及作为假体的冠和桥的正畸装置的部件。由于这种在其表面上形成的氧化钛薄膜,Ti-6a1-4v是型牙科应用的耐腐蚀合金。然而,炎症条件AD蛋白质存在可能影响该合金的耐腐蚀性。我们的研究工作旨在探讨白蛋白和炎症条件对唾液素梅尔生物溶液中Ti-6a1-4V的耐腐蚀性的影响。为了模拟在体外研究中的血液血液炎性病症,通过加入过氧化氢(反应性氧物质,在炎症期间发现)和白蛋白是生物流体最典型的蛋白质。施用电化学方法进行腐蚀研究。结果提供了证据,即钛合金耐腐蚀性受到唾液生物溶液中炎症条件和白蛋白存在的影响。

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